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Date Published: 12/04/2023
Abstract Views: 376
Views PDF: 175
DOI: https://doi.org/10.51298/vmj.v525i1A.4948
Issue
Vol. 525 No. 1A (2023)
Section
Các bài báo
How to Cite
Nguyễn, V. H. Y. ., Phạm , T. L. ., Trịnh , T. T. ., Trần , T. M. N. ., Lương , H. L. ., Lê, H. P. ., Nguyễn, T. M. K. ., Đỗ , T. D. L. ., Bùi , P. Điệp ., Lê, M. H. ., Nguyễn, T. H. N. ., Nguyễn, T. T. ., Lê, T. Y. N., Đào , T. Q. C., & Huỳnh , M. T. . (2023). EFFECT OF PREOPERATIVE BATHING WITH 4% CHLORHEXIDINE GLUCONATE IN REDUCING SKIN BACTERIAL LOAD: A LONGITUDINAL STUDY IN UNIVERSITY MEDICAL CENTER AT HCMC. Vietnam Medical Journal, 525(1A). https://doi.org/10.51298/vmj.v525i1A.4948

EFFECT OF PREOPERATIVE BATHING WITH 4% CHLORHEXIDINE GLUCONATE IN REDUCING SKIN BACTERIAL LOAD: A LONGITUDINAL STUDY IN UNIVERSITY MEDICAL CENTER AT HCMC

Vũ Hoàng Yến Nguyễn1, Thị Lan Phạm 1, Thị Thoa Trịnh 1, Thị Mỹ Nhung Trần 2, Hồng Loan Lương 1, Hồng Phước Lê3, Thị Minh Khai Nguyễn1, Thị Diệu Linh Đỗ 1, Phi Điệp Bùi 1, Mộng Hảo Lê1, Thị Hằng Nga Nguyễn1, Thanh Tuyền Nguyễn1, Thị Yến Nhi Lê1, Thị Quỳnh Châu Đào 1, Minh Tuấn Huỳnh 3,
1 University of Medicine and Pharmacy at Ho Chi Minh City hospital
2 Vietnam Medical Equiment Corporation Company Limited.
3 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Objectives: Preoperative bathing with 4% Chlorhexidine Gluconate (4%-CHG) has been considered an effective solution to prevent surgical site infection (SSI). This study aims to evaluate the impact of preoperative chlorhexidine bathing on the skin bacterial load. Methods: A longitudinal study was conducted from May 2020 to December 2020 at University Medical Center at HCMC. Participants were patients who underwent surgery during study periods. A mandatory procedure for showering with 4%-CHG at two time points before surgery was implemented. Bacterial loads in Colony Forming Unit per square centimeters (CFU/cm2) on the skin of armpit, groin, and navel areas were tested at three time points including before and after the second bathing, and at the time when patients were transported to the operating room. Data on patient’s characteristics, adherence to bathing procedure, and the waiting time between bathing and surgery was collected. Results: A total of 2,476 specimen swabs were collected from 280 patients. The steadily decline trends of skin bacterial load over time were observed (p for trend of log10CFU<0.001). On armpit skin, bacterial load gradually decreased from 43.1 CFU/cm2 before the second bathing to 3.8 CFU/cm2 after that and to 1.3 CFU/cm2 at time of transportation for surgery. A similar decline trend was observed in groin and navel areas (respectively,  25.0, 6.3, 3.8 CFU/cm2 and 12.5, 0.0, 0.0 CFU/cm2). Conclusions: Preoperative bathing with 4% Chlorhexidine Gluconate effectively reduces bacterial load on the skin which has shown to be a potential implementation on the prevention of surgical site infections.

Article Details

Keywords

Chlorhexidine bathing, preoperative bathing, skin bacterial load.

References

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