THE EFFECTIVENESS OF THE MANAGING CARDIOVASCULAR DRUG- DISEASE INTERACTIONS IN INPATIENTS THROUGH THE DRUG INTERACTIONWARNING SYSTEM AND CLINICAL PHARMACY ACTIVITY IN SAINT PAUL GENERAL HOSPITAL

Thành Hải Nguyễn1, Thu Phương Trần 1, Đình Tùng Đỗ 2,, Tứ Sơn Nguyễn1, Thị Dừa Nguyễn2, Bích Hạnh Vũ 3, Đình Hiến Nguyễn3
1 Hanoi University of Pharmacy
2 Xanh Pon hospital
3 Xanh pon hospital

Main Article Content

Abstract

Objectives: To evaluate the effectiveness of managing cardiovascular drug-disease interactions in inpatients through the drug interaction warning system and clinical pharmacy activity in Saint Paul General Hospital. Results: This research was designed as an intervention study. The results showed that the patients in this study were elderly (mean age: 67.2 ± 14.4 in the pre-intervention period and 53.0 ± 8.6 in the intervention period), using many drugs in both stages, respectively: 7.6 ± 2.0 and 6.2 ± 1.3. After the pharmacist intervened, the number of cardiovascular drug-disease interactions reduced from 71 (1.055%) to 7 (0.101%). Interaction pairs that still occurred after interfering were: clopidogrel - peptic ulcer with bleeding, thiazide diuretics - severe renal failure, and aspirin - peptic ulcer without bleeding. The consensus between physicians and pharmacists handled these interactions. Conclusion: The drug-disease interaction warning system and clinical pharmacy activity have managed all pairs of interactions that often occur on inpatients in Saint Paul General Hospital.

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References

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