ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG CỦA BỆNH NHÂN UNG THƯ VÚ THỂ DỊ SẢN TẠI BỆNH VIỆN K

Abstract

Aim: The objective of this study was to assess the clinical and preclinical charecteristics of patients diagnosed with metaplastic breast cancer in Vietnam National Cancer Hospital. Patients and methods: The study was designed as a retrospective and prospective study, in which 52 patients were diagnosed with metaplastic breast cancer in Vietnam National Cancer Hospital from Jan 2019 to Jun 2022. We assessed clinicopathology characteristics of this group. Results: The mean tumor size was 3.7 ± 0,3 cm. 46.15% patients had lymph node metastasis (53.85%). Triple negative breast cancer accounted for the highest proportion with 75%. Besides, 15.38% had hormone receptor positive and HER2 negative, and 9.62% patients with hormone receptor positive and HER2 positive. On mammogram, only 10 patients (19.23%) with typical spiculated soft tissue mass and 9 patients (17.31%) with microcalcifications. In addition, only 20 patients (38.5%) had a typical image of breast cancer on ultrasound. Conclusions: In our study, metaplastic breast cancer is often detected when the tumor size was large, the patient was at a late stage, and the most common immunohistochemical feature was triple negative breast cancer, suggesting that this type of invasive breast cancer has a poor prognosis.