COLONIC ADENOCARCINOMA WITH YOLK SAC TUMOR: A RARE CASE REPORT AND LITERATURE REVIEW

Thị Tuyết Hạnh Ngô 1,2,3, Văn Tấn Phạm 1,, Phúc Thục Uyên Nguyễn1, Hòa Nhơn Nguyễn2, Đình Được Diệp2, Quốc Trung Lâm 3, Quang Thông Phạm 4
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Nguyen Tri Phuong hospital
3 University of Medicine and Pharmacy at Ho Chi Minh City hospital
4 Cho Ray hospital

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Abstract

Cases of colonic adenocarcinoma with yolk sac tumor are very rare. Only a few cases have been reported in the literature. We reported a case of 29-years-old male patient with no clinical symptoms who was incidentally diagnosed with a mesenteric tumor. The results of abdominal computed tomography with contrast revealed a soft tissue mass in the ascending mesentery, size 95x88 mm, multi-arch margin and loss of boundary with the ascending colon; The ascending colon has a site of loss of layer structure, imaging suggests the diagnosis of a mesenteric tumor or metastatic colonic cancer. Colonoscopy showed an infiltrative tumor in the transverse colon, that narrowed the colon lumen. The result of colonoscopy was suspicious for colon cancer. The patient's AST, ALT, GGT, CEA and CA 19-9 serum tests were within normal limits. However, serum AFP was elevated (42345 ng/ml). The patient underwent retroperitoneal tumor resection and right hemicolectomy. Macroscopically, there were tumors in the colonic mucosa and mesentery. Histopathological diagnosis after immunohistochemical staining: Moderate differentiated colonic adenocarcinoma with yolk sac tumor and tumor invades through the muscularis propria into pericolonic tissue.

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References

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