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Date Published: 20/04/2023
Abstract Views: 351
Views PDF: 177
DOI: https://doi.org/10.51298/vmj.v525i1B.5144
Issue
Vol. 525 No. 1B (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. H. ., & Nguyễn, V. H. . (2023). EVALUATION ON UNWANTED EFFECTS OF R-GDP REGIME IN TREATMENT OF B CELL NON HODGKIN LYMPHOMA RELAPSED AT BACH MAI HOSPITAL. Vietnam Medical Journal, 525(1B). https://doi.org/10.51298/vmj.v525i1B.5144

EVALUATION ON UNWANTED EFFECTS OF R-GDP REGIME IN TREATMENT OF B CELL NON HODGKIN LYMPHOMA RELAPSED AT BACH MAI HOSPITAL

Tuấn Hùng Nguyễn1, Văn Hưng Nguyễn1,
1 Bach Mai hospital

Main Article Content

Abstract

Objectives: To  evaluate  the  side  effects  of  R- GDP regimen of  treating  B cell non Hodgkin lymphoma relapsed. Objects and Methods: Cross-sectional description on 61 patients with relapsed B-cell non Hodgkin lymphoma treated with R-GDP regimen at Hematology and Blood Transfusion Center, Bach Mai Hospital from January 2013 to July 2021. Results and conclusions: 61 patients treated for 251 cycles with R-GDP regimen. Clinical undesirable effects: nausea - vomiting grade I and II: 41.4% and 25.1%. Rarely symptoms: diarrhea, chills, inflammation of the oral mucosa. On the hematopoietic system: leukopenia, thrombocytopenia grade III - IV were: 63.4% and 40.7% of cycles, grade III - IV hemoglobin reduction was 17.1%. On liver and kidney: the rate of cycles without affecting renal function urea and creatinine was 85.7% and 82.1%, the rate of cycles without increasing AST and ALT was 82.1 and 80.5%.

Article Details

Keywords

non Hodgkin lymphoma, R- GDP regimen

References

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