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A CASE REPORT OF ADVANCED HEPATOCELLULAR CARCINOMA TREATED WITH HEPATIC ARTERIAL INFUSION CHEMOTHERATY
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Abstract
Hepatic arterial infusion chemotherapy (HAIC) is widely used in Japan, Korea, for relatively high effectiveness in treatment of locally invasive (vascular invasion) Hepatocellular carcinoma (HCC) and especially for patients with Child-Pugh B cirrhosis. It increases the survival time of patients with advanced HCC and reduces systemic side effects. Currently, the method is being applied in some hospitals in VietNam. We report a case where HAIC was performed, treating locally advanced HCC. After the intervention, the patient significantly reduced tumor size and portal vein thrombosis after only 4 courses of chemotherapy according to the Low-dose FP regimen. After this clinical case, we found that HAIC has a good effect in the treatment of locally advanced HCC.
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Keywords
Hepatic arterial infusion chemotherapy, advanced HCC, low-dose FP regimen
References
2. Llovet JM, Ricci S, Mazzaferro V, et al. Sorafenib in advanced hepatocellular carcinoma. N Engl J Med. 2008;359(4):378-390.
3. Cheng AL, Qin S, Ikeda M, et al. Updated efficacy and safety data from IMbrave150: Atezolizumab plus bevacizumab vs. sorafenib for unresectable hepatocellular carcinoma. Journal of Hepatology. 2022; 76(4):862-873.
4. Nishikawa H, Osaki Y, Kita R, Kimura T. Hepatic Arterial Infusion Chemotherapy for Advanced Hepatocellular Carcinoma in Japan. Cancers (Basel). 2012;4(1):165-183.
5. Moriguchi M, Aramaki T, Nishiofuku H, et al. Sorafenib versus Hepatic Arterial Infusion Chemotherapy as Initial Treatment for Hepatocellular Carcinoma with Advanced Portal Vein Tumor Thrombosis. Liver Cancer. 2017; 6(4):275-286.
6. Long GB, Xiao CW, Zhao XY, Zhang J, Li X. Effects of hepatic arterial infusion chemotherapy in the treatment of hepatocellular carcinoma. Medicine (Baltimore). 2020;99(26):e20745.
7. Tsai WL, Lai KH, Liang HL, et al. Hepatic Arterial Infusion Chemotherapy for Patients with Huge Unresectable Hepatocellular Carcinoma. PLoS One. 2014;9(5):e92784.