RESEARCH ON BETA CELL FUNCTION, INSULIN SENSITIVITY AMONG PRE-DIABETES POPULATION IN HANOI, VIETNAM

Đình Tùng Đỗ1,, Phoong Phu Vông Khăm2, Văn Bình Tạ3, cs
1 Xanh pon hospital
2 103 Military Hospital-Lao
3 Hanoi medical university

Main Article Content

Abstract

Studying beta cell function, insulin sensitivity, and insulin resistance by HOMA2 software. In Vietnam, published data using HOMA2 software to study beta cell function, insulin sensitivity, and insulin resistance in pre-diabetes are limited. To serve as a basis for broader studies in overweight, obese, diabetic, and hypertensive, we studied 513 subjects (85 normal people and 428 people with pre-diabetes) aged, from 18 to 69, showed that: in people with pre-diabetes, β-cell function, insulin sensitivity, insulin resistance are: 79.1±29.9 and 128.6±55.8, respectively; insulin sensitivity decreased by 19.7% compared to the control group (128.6±55.8 vs. 160.1±53.85, p<0.001), however the beta cell function between the two groups did not differ. statistical significance (79.1±29.9 versus 79.5±23.9); The index of insulin resistance in the pre-diabetes group was higher than that in the control group (0.98±0.56 versus 0.72±0.32, p<0.001).

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