KẾT QUẢ CỦA CAN THIỆP NHẰM TỐI ƯU SỬ DỤNG KHÁNG SINH DỰ PHÒNG TẠI KHOA NGOẠI THẦN KINH – BỆNH VIỆN NGUYỄN TRI PHƯƠNG

Abstract

Background: Evaluation of surgical antimicrobial prophylaxis use in Department of Neurosurgery, Nguyen Tri Phuong Hospital. Subjects and methods: A retrospective Cross-sectional study on 157 hospitalized-patients who underwent general surgery in Department Neurosurvery, Nguyen Tri Phuong Hospital, in two stages 02/2018-05/2018 and 06/2020-08/2020. Interventions include: promulgating and applying standardized antibiotic prophylaxis guidelines and deploying clinical pharmacist to support doctors and nurses in prescribing, dose. Results: The average age of patients in two evaluations was 54.8 ± 15.6, the majority of patients were female (52.2%), spine surgery (68.8%), programmed surgery (85.4%), clean surgery (96.2), ASA score <3 (83.4%), the difference was not statistically significant. The cost of antibiotics decreased (saved VND 376 000, saving 44.74%, p < 0.05). The length of hospital stay decreased from 11.8 days to 7.6 days, the difference was statistically significant. In 2018, statistical dates showed 100% using antibiotics prophylaxis were unsuitable with the treatment regimen. However, in 2020, the selection of antibiotics prophylaxis is more suitable, ceftazolin is used more in surgery, the reasonable rate is 100% in terms of dose, route of administration and duration of use after surgery. Conclusion: The issuance of the prophylactic antibiotic guideline and the deployment of pharmacists in the ward contributed to the optimal use of prophylactic antibiotics at the ward.