EVALUATING THE CHANGE OF FENO LEVELS DURING THE TREATMENT OF ASTHMA

Thị Hạnh Phan 1,, Thu Phương Phan 1,2
1 Bach Mai hospital
2 Hanoi medical university

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Abstract

Objective: To evaluate the change of FENO during the treatment of asthma in outpatient treatment at the Respiratory Center - Bach Mai Hospital. Methods: prospective cohort study of 70 outpatients at the chronic lung disease management clinic - Bach Mai Hospital from August 2021 to August 2022. Results: Among 70 patients participating in the study, after 3 months of treatment, the mean value of FENO decreased from 25.2 ± 18.1 to 18.6 ± 13.8, ACT increased from 16.9 ± 4, 8 to 19.2 ± 3.9. The FENO level was different between the fully controlled, partially controlled, and uncontrolled asthma groups. There is no correlation between percentage change of FEV1- FENO - ACT after 03 months. FENO is valuable in differentiating of eosinophil elevation (>300 cells/microliter), cut-off value of 10.5ppb, sensitivity 84.8%, specificity 69.2%. Conclusion: FENO was related to the level of asthma control according to the ACT questionnaire. FENO is valuable in detecting eosinophilia.

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References

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