KẾT QUẢ PHẪU THUẬT CẮT THANH QUẢN BÁN PHẦN TRONG ĐIỀU TRỊ UNG THƯ THANH QUẢN TẠI BỆNH VIỆN ĐẠI HỌC Y DƯỢC TP.HCM TỪ 2018 ĐẾN 2021

Abstract

Background: Laryngeal cancer is a common type of head and neck cancer. The success of laryngeal preservation methods in partial laryngectomy for laryngeal cancer treatment is not only meaningful in the resolution of the disease, but also in preserving laryngeal function and improving the quality of life of patients. Objectives: Survey on surgical outcomes of patients with laryngeal cancer after partial laryngectomy and find out some factors related to surgical results. Method: The study was carried out on 38 laryngeal cancer patients undergoing partial laryngectomy at the University Medical Center HCMC from January 1, 2018 to December 31, 2021 and monitor the patient's recurrence and death. Result: The majority were male, accounting for 92.1% with the mean age of 63.0 ± 8.8 years. Surgical methods including oral laser microsurgery were 13.2%, partial laryngectomy was 86.8%. The mean postoperative hospital stay was 7.4 ± 4.4 days. The laser microsurgery group had a shorter postoperative hospital stay than the open surgery group with p < 0.005. The most postoperative complications were pneumothorax 13.1%, pneumonia was 7.9%; surgical site effusion and wound infection were 5.3%; Throat fistula, bleeding and bronchitis were all 2.6%. The results of distant follow-up showed that the recurrence rate was 7.9%. 100% of patients survived, no patients died. The mean disease-free survival time was 3.7 years, the disease-free survival rate after 3 years was 90.8%. The mean disease-free survival time of the N0 group was longer than that of the N1 group, the stage I and II groups were statistically significantly longer than the stage III with p < 0.05. Conclusion: Partial laryngectomy to treat early laryngeal cancer is safe and effective, helping patients to preserve the larynx while still achieving the goal of treatment.