NGHIÊN CỨU ĐẶC ĐIỂM NỒNG ĐỘ FT3, FT4, TSH HUYẾT TƯƠNG VÀ HÌNH THÁI TUYẾN GIÁP Ở BỆNH NHÂN RỐI LOẠN LƯỠNG CỰC TÁI PHÁT CƠN HƯNG CẢM

Abstract

Objectives: Characterization of hormone levels FT3, FT4, TSH and thyroid morphology in patients with bipolar disorder relapsing manic episodes. Subjects and methods: Includes 45 patients with confirmed bipolar disorder, current relapse with manic episodes diagnosed according to DSM-5 criteria (2013), inpatient treated at Psychiatric Department, Military Hospital 103 from March 2022 to November 2022. Test the plasma levels of FT3, FT4, TSH hormones and ultrasound to assess thyroid morphology in subjects, analyze the results using SPSS 26.0 software. Results: The average concentration of hormones FT3, FT4, TSH in the plasma of the study group was 3.10 ± 0.53 pg/mL, 0.96 ± 0.14 ng/dL and 1,52 ± 1.31mIU/L respectively. There was no difference in plasma concentrations of the hormones FT3, FT4, and TSH according to age, sex, age of onset, and duration of illness in patients with bipolar disorder relapsing manic episodes. The majority of patients had no changes in thyroid morphology on ultrasound. Conclusions: There was no change in hormone levels and thyroid morphology in patients with bipolar disorder with recurrent manic episodes.