ASSESSING THE PRELIMINARY RESULT OF INDUCTION TCF-REGIMEN CHEMOTHERAPY IN LOCALLY ADVANCED SQUAMOUS CELL HEAD AND NECK CANCER
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Abstract
Objective: Assessing treatment response and analysing several factors affecting response rate of induction TCF-regimen chemotherapy in patients with locally advanced squamous cell head and neck cancer at K Hospital. Patients and method: Retrospective and prospective analysis of 47 patients with locally advanced squamous cell head and neck cancer who were treated with induction TCF-regimen chemotherapy at K Hospital from January 2019 to December 2022. Results: Of 47 patients, majority of patients were male (74.5%) with age < 65 years old (68.1%). ECOG performance status 0 was reported in 38.3%. Stage IV (M0) was observed in 78.7%. Hypolaryngeal and laryngeal cancers were observed in 44.7%, then oropharyngeal cancer (accounted for 34%). Overall response rate of induction TCF-regimen chemotherapy was seen in 70.2%. Conclusion: Induction TCF-regimen chemotherapy for the treatment of locally advanced squamous cell head and neck cancer had a high overall response rate.
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Keywords
squamous cell head and neck cancer, locally advanced, induction chemotherapy, TCF
References
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