THE RELATIONSHIP BETWEEN VALUE OF REGIONAL SARTURATION OF OXYGENATION (rSO2) TO THE CLINICAL AND RADIOLOGY FINDING IN SEVERE MCA STROKE PATIENT
Main Article Content
Abstract
Near Infra Red Spectroscopy NIRS is a noninvasive technique to measure the oxygen sarturation in the brain surface. The primary device only monitor the change of sarturation, then the advanced technique can monitor the absoluted value of brain oxygenation (Sarturation cerebral oxygenation-ScO2). The normal range of ScO2 from 58-82%, can be reduced to 10% depended on the lesion or pathology. We conducted the study to apply this technique on middle cerebral artery MCA) occlusion patient at the emergency center at Bachmai hospital. The result showed: the lesion side of MCA ischemic had the lower value of rSO2 than the normal side of the brain significantly statitic, (p < 0,05). In the patient who had artery resolution (recanal): rSO2 at 24h greater than on admission, while the value had no change in the unresolved group. With the cutoff point at rSO greater than 62%, 100% patient had artery resolution, otherwise 27,3% unresolved. The group who underwent thrombobectomy had recanalization on 24h, rSO2 ≥ 62% if NIHSS < 10 compare to NIHSS >10; OR=0,057 (95% CI:0,006-0,588), p < 0,05. Conclusion: Regional oxygen sarturation value has been proved to be a predict factor to the lesion side and the restoration in MCA stroke patient.
Article Details
Keywords
MCA occlusion, regional sarturation oxygenation (rSO2), NIRS
References
2. Lê Văn Thính. Nhồi máu não,Trong cuốn Hướng dẫn chẩn đoán và xử trí tai biến mạch máu não. Lê Đức Hinh Và nhóm chuyên gia, Nhà xuất bản Y học.2008: 217-224.
3. Siesjo B.K. Cerebral circulation and metabolism. Journal of Neurosurgery.1984;60: 883-908.
4. Maragos W. F. Mitochondrial uncoupling as a potential therapeutic target in acute central nervous system injury. J Neurochem.2004; 91: 257-262.
5. Demet GG, Talip AA, Nevzat UU et al. The evaluation of cerebral oxygenation by oximetry in patients with ischaemic stroke. J Postgrad Med. 2000;46:70-74
6. Ádám Annus, András Nagy, László Vécsei, et al. 24-hour near-infrared spectroscopy monitoring of acute ischaemic stroke patients undergoing thrombolysis or thrombectomy: a pilot study.Journal of Stroke and Cerebrovascular Diseases.2019;28(8):2337-2342.
7. Ritzenthaler T, Cho TH, Mechtouff L, et al. Cerebral NearInfrared Spectroscopy: A Potential Approach for Thrombectomy Monitoring. Stroke. 2017;48(12):3390-2
8. Lương Quốc Chính. Nghiên cứu hiệu quả kết hợp dẫn lưu và sử dụng Alteplase não thất trong điều trị chảy máu não thất có giãn não thất cấp, Luận án Tiến sĩ y học, Trường Đại học Y Hà Nội, Hà Nội.2017