EPIDEMIOLOGICAL CHARACTERISTICS, RISK FACTORS OF MENINGOCOCCAL AND POPULAR SEROGROUPS

Xuân Kiên Nguyễn1,2,, Văn Ba Nguyễn1,2
1 103 hospital
2 Vietnam Military Medical Academy

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Abstract

Objectives: To describe the epidemiological characteristics, risk factors of Meningococcal in some key areas. Subjects and methods: a cross-sectional descriptive study, sampling and testing by ELISA method to detect anti- N. meningitidis antibodies on 21,630 serum samples collected from 3 regions of the Northwest, the Central Highlands and the Southwest. Results: The percentage of people carrying anti-meningococcal antibodies in the Northwest region was 7.94%, higher than in other regions, this difference was statistically significant, with p < 0.05. The proportion of people with anti-meningococcal antibodies in the Central Highlands was: 4.19%, higher than the infection rate in the Southwest region of 1.90%. This difference is statistically significant, with p<0.05. The rate of people infected with meningococcal disease in all 3 regions was 4.61%. The lowest rate of people infected with meningococcal disease in the 36-55 age group was 4.53%. Highest in age group from 56-65: 5.88%. The difference was statistically significant, with p<0.05. People working in agriculture, forestry, farming, farming and soldiers have a higher rate of meningococcal infection than those working in self-employed and other occupations, the difference is statistically significant with p < 0.05. The rate of pathogenic serogroups (including B and C) in 3 regions was 92.31%. The lowest is the Southwest (57.14%), the highest is the Central Highlands (100%). This difference is statistically significant (p(2;3) < 0.01). The structure of serogroup B infection in all 3 regions accounts for a high rate (85.90%). Serogroup C was found in the Northwest (11.90%) and the Southwest region (6.41%). Conclusion: The overall prevalence of anti- N. meningitidis antibody carriers was 4.61%. There are differences in the rate of infected people across regions, ages, occupations and regions. Serogroup B and C accounted for 92.31%.

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References

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