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Date Published: 16/05/2023
Abstract Views: 385
Views PDF: 131
DOI: https://doi.org/10.51298/vmj.v526i1A.5313
Issue
Vol. 526 No. 1A (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. T. H. ., Nguyễn, T. T. ., & Vũ , T. T. . (2023). THE RELATIONSHIP BETWEEN N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDE AT ADMISSION AND CARDIOVASCULAR EVENTS IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION. Vietnam Medical Journal, 526(1A). https://doi.org/10.51298/vmj.v526i1A.5313

THE RELATIONSHIP BETWEEN N-TERMINAL PRO-B-TYPE NATRIURETIC PEPTIDE AT ADMISSION AND CARDIOVASCULAR EVENTS IN PATIENTS WITH NON-VALVULAR ATRIAL FIBRILLATION

Thị Thu Hoài Nguyễn1,2,, Thị Thủy Nguyễn3, Thị Thơm Vũ 2
1 Bach Mai hospital
2 VNU - School of Medicine and Pharmacy
3 Hanoi medical university

Main Article Content

Abstract

Background: Atrial fibrillation (AF), the most common cardiac rhythm abnormality, increases cardiovascular events such as death, stroke, systemic embolism, heart failure. Plasma N-terminal pro-B-type Natriuretic Peptide (NT-proBNP) level is an independent prognostic factor capable of predicting cardiovascular events in patients with non-valvular atrial fibrillation. Aim: To study the relationship between plasma NT-proBNP level at admission and cardiovascular events in patients with non-valvular AF. Methods: 200 patients with non-valvular AF were tested for NT-proBNP at admission. All patients were followed on 6 months. We studied the relationship between NT-proBNP and the rate of hospital re-admission due to cardiovascular events. Results: The NT-proBNP level in the group of general cardiovascular events was higher than non-event group (1024,98 ± 1204,36 pmol/l vs 161,31 ± 207,92 pmol/L, p = 0.000. Each increase of 100pmol/L concentration of NT-proBNP, the general cardiovascular event increased 2.5 times (OR = 2,513; 95%CI 1,561 - 2,821; p = 0,000. At cut-off 311 pmol/L, AUC 0.848, sensitivity, specificity, positive predictive value, negative predictive value: 70%; 91%; 83%; 83%, respectively). Conclusion: NT-proBNP is an independent prognostic factor in patients with atrial fibrillation non-valvular heart disease.

Article Details

Keywords

Atrial fibrillation, non-valvular atrial fibrillation, NT-proBNP

References

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