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Date Published: 16/05/2023
Abstract Views: 321
Views PDF: 141
DOI: https://doi.org/10.51298/vmj.v526i1A.5334
Issue
Vol. 526 No. 1A (2023)
Section
Các bài báo
How to Cite
Triệu , V. M. ., Lưu , T. B. ., Hoàng, V. T. ., Hoàng, V. Đệ ., Nguyễn, L. T. ., Nguyễn, L. T. ., & Ngô , T. G. . (2023). HUMAN PARVOVIRUS B19 INFECTION RATE AND RELATIONSHIP TO EPIDEMIOLOGICAL AND SUBCLINICAL FEATURES IN PATIENTS WITH RHEUMATOID ARTHRITIS. Vietnam Medical Journal, 526(1A). https://doi.org/10.51298/vmj.v526i1A.5334

HUMAN PARVOVIRUS B19 INFECTION RATE AND RELATIONSHIP TO EPIDEMIOLOGICAL AND SUBCLINICAL FEATURES IN PATIENTS WITH RHEUMATOID ARTHRITIS

Văn Mạnh Triệu 1,2, Thị Bình Lưu 2, Văn Tổng Hoàng1, Văn Đệ Hoàng1, Lĩnh Toàn Nguyễn1, Lĩnh Toàn Nguyễn1, Trường Giang Ngô 1,
1 Vietnam Military Medical Academy
2 ThaiBinh University of Medicine and Pharmacy

Main Article Content

Abstract

Objectives: To evaluate the prevalence of Human Parvovirus B19 virus infection in relation to epidemiological characteristics and some main subclinical manifestations in rheumatoid arthritis patients. Subjects and methods: 115 patients with rheumatoid arthritis were collected peripheral blood samples were, separated plasma, detected B19_IgG, and B19-IgM antibodies by ELISA method, the calculated infection rate was and compared the difference epidemiological characteristics and some main clinical manifestations between negative and positive with antibodies to the Parvovirus B19 virus groups. Results: The rate of B19_IgG positivity was 42.6%, B19_IgM was 2.6%; the positive rate was 69.4% for females, 30.6% for males; The highest positive rate was in the age group 60-69 years old (36.7%). Conclusion: The rate of Parvovirus B19 virus infection in rheumatoid arthritis patients was higher than the control group (42.6% vs 26.7%, p = 0.018). The prevalence of this infection is higher in the group of female rheumatoid arthritis patients. Parvovirus B19 infection may play a role in the pathogenesis of rheumatoid arthritis.

Article Details

Keywords

Parvovirus B19 virus; Rheumatoid arthritis; Relationship

References

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