ASSESSMENT OF LEFT VENTRICULAR MASS AND FUNCTION IN HYPERTHROPHIC CARDIOMYOPATHY PATIENTS BY THREE-DIMENSIONAL ECHOCARDIOGRAPHY
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Abstract
Aims: To investigate left ventricular mass (LVM) and volume and function in patients with hypertrophic cardiomyopathy using three-dimensional echocardiography (3DE). Methods: From 6/2018 to 6/2021, patients diagnosed with hypertrophic cardiomyopathy were recruited into the study. All patients underwent clinical examination and 2D/3D echocardiography at the Vietnam National Heart Institute, Bach Mai hospital. LVM and LV volumes (EDV, ESV) and LVEF on 2D echocardiography and 3DE were assessed according to the 2015 American Society of Echocardiography guidelines. Results: Fourty-eight patients were included into the study: 22 men (45.8%), 26 women (54.2%), mean age 43,7 ± 22,3, 89.6% patients had S.A.M, 45.8% patients had mid-systolic aortic closure, 43,8% patients had elevated left ventricular outflow tract gradient (≥30 mmHg). 45.8% patients had diffused ventricular septal hypertrophy, 29.2% patients had mid-ventricular septal hypertrophy, 16.7% patients had concentric hypertrophy, 12,5% patients had apical hypertrophy. On 3DE, mean end-diastolic LV volume was 66,8 ± 24,7 (ml), mean end-systolic LV volume was 18,1 ± 10,7 (ml), mean LVEF was 74,07 ± 7,1 (%), mean LV mass was 189,7 ± 97,8 (gr). LV mass assessed by 3DE was significantly lower than LV mass assessed by time-motion (TM) echocardiography, p = 0.000. Conclusions: Three-dimensional echocardiography is safe and a non-invasive imaging method which is helpful in the evaluation of morphology and function and mass of left ventricle in patients with hypertrophic cardiomyopathy. 3DE-LVmass was was significantly lower than TM-LVmass, p =0.000.
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Keywords
hypertrophic cardiomyopathy, three-dimensional echocardiography, left ventricular function, left ventricular mass
References
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