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Date Published: 16/05/2023
Abstract Views: 242
Views PDF: 115
DOI: https://doi.org/10.51298/vmj.v526i1A.5365
Issue
Vol. 526 No. 1A (2023)
Section
Các bài báo
How to Cite
Lê, T. D. ., & Thân , V. S. . (2023). SPLEEN VOLUME CHANGE AFTER PORTOHEPATIC VEIN EMBOLIZATION FOR LIVER HYPERTROPHY IN HEPATOCELLULAR CARCINOMA. Vietnam Medical Journal, 526(1A). https://doi.org/10.51298/vmj.v526i1A.5365

SPLEEN VOLUME CHANGE AFTER PORTOHEPATIC VEIN EMBOLIZATION FOR LIVER HYPERTROPHY IN HEPATOCELLULAR CARCINOMA

Thanh Dũng Lê1,2,3,, Văn Sỹ Thân 2,4
1 Viet Duc hospital
2 Hanoi medical university
3 VNU Hanoi-University of Medicine and Pharmacy
4 Viet DUc hospital

Main Article Content

Abstract

Objective: To identify and describe changes in spleen volume occurring in patients with hepatocellular carcinoma (HCC) after portohepatic vein embolization (LVD). Materials and methods: Thirty-two consecutive patients (26 men and 6 women, with a median age of 55.5) with HCC who underwent LVD between October 2021 and December 2022 were included. One female patient was excluded due to receiving partial splenic artery embolization before LVD to treat thrombocytopenia due to hypersplenism. Thus, 31 patients were included in the study. Liver and spleen volumes were measured by computed tomography (CT) volumetry on the most recent CT before LVD and within 1 - 3 months after LVD. Results: Thirty-one patients (100%) demonstrated increased spleen volume on the post-procedure CT. The increase in spleen volume on CT after LVD was statistically significant compared to before LVD (median value after LVD was 223.3 versus 185.7 ml, p < 0.001). Spleen volume increased by an average of 21.5% within three months of LVD. No LVD procedure-associated complications occurred. %FLR was 29.41% (interquartile range (IQR) of 7.61) and 48.93% (IQR of 8.62) before and after LVD, respectively (p < 0.001). The degree of hypertrophy and the kinetic growth rate was 14.86% (IQR of 8.43) and 16.8 %/week (IQR of 20.5), respectively. Conclusions: Splenic enlargement after LVD in HCC patients is a common finding on CT. Increased familiarity amongst radiologists of this phenomenon as likely reflecting physiological changes is important to avoid unnecessary evaluation for underlying conditions causing interval enlargement of the spleen.

Article Details

Keywords

hepatocellular carcinoma, liver hypertrophy, splenomegaly.

References

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