MỐI LIÊN QUAN GIỮA MỘT SỐ YẾU TỐ NGUY CƠ TĂNG ĐÔNG VÀ TỔN THƯƠNG NÃO TRONG BỆNH HUYẾT KHỐI TĨNH MẠCH NÃO

Abstract

Objective: To analysis the relationship between hypercoagulation risk factors and magnetic resonance imaging of cerebral venous thrombosis. Subjects and methods: A prospective, descriptive study of 38 patients with cerebral venous thrombosis treated at the Neurology Center, Bach Mai Hospital from March 2020 to June 2021. Results: The mean age was 42.4 ± 14.8, the male/female ratio was 1.2:1. The rate of anticoagulant proteins (PC, PS, ATIII) deficiency associated with primary hypercoagulability was 39.5%, of which protein S deficiency was the most common (21.1%), followed by protein C and ATIII deficiency (18,4% and 10.5%, respectively). The risk factors of secondary hypercoagulation related to antibodies were found with a low rate, of which antiphospholipid antibodies percentage was the highest (5.3%), other antibodies with lower proportion were antinuclear antibodies ANA (2.6%), anti-dsDNA antibodies (2.6%), anti-cardiolipin antibodies (2.6%). There was no association between hypercoagulation risk factors with brain parenchymal damage and the site of thrombosis. Conclusions: The rate of anticoagulant proteins (PC, PS, ATIII) deficiency associated with primary hypercoagulability was 39.5%, of which protein S deficiency was the most common (21.1%). The risk factors for secondary hypercoagulation related to antibodies were found with a low rate. There was no association between hypercoagulation risk factors with brain parenchymal damage and the site of thrombosis.