ĐẶC ĐIỂM TỔN THƯƠNG KHỚP TRÊN X-QUANG CỦA BỆNH NHI HEMOPHILIA TẠI BỆNH VIỆN NHI ĐỒNG 1

Abstract

Objectives: Describe characteristics of hemophilic arthropathy on X-ray films of pediatric patients with hemophilia and describe epidemiological, history, and clinical features of patients with and without hemophilic arthropathy on X-ray films. Subjects: Children with hemophilia, under 16 years old, treated in Hematology Department in Children Hospital 1 from July 2021 to August 2022. Methods: Case series reports, 42 patients with clinical joint symptoms and/or joint damages on ultrasonography underwent joint radiographs. Results: Among 42 patients, the rate of joint damage was 64.2%. In 150 joints surveyed, the rate of joint damage was 51,3%. Knee arthropathy was the most prevalent (41,5%), followed by ankle arthropathy (38,9%). The most common lesions were osteoporosis (52,4%), followed by bone hypertrophy (35,7%). The mean age of hospitalization of the group with arthropathy on X-ray (9,5 years old) was higher than that of the uninjured group (7,4 years old). The number of hospitalizations in the past 12 months for joint bleeding from 4 to 6 times was statistically different in the hemophilia group with joint damage compared with the hemophilia group without joint damage. The age at admission and the number of hospitalizations for joint bleeding were positively correlated with the Pettersson score. Conclusions: The rate of hemophilic arthropathy in 42 pediatric patients with hemophilia was 64,2% based on joint radiographs. Commonly injured joints are knee joints 41,5%, and ankle joints 38,9%. Common lesions of hemophilic arthropathy are osteoporosis, followed by hypertrophy of the ends of the bones. Age at admission and the number of hospitalizations for hemarthroses were positively correlated with the Pettersson score.