DIAGNOSTIC RATE OF OSTEOPOROSIS IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED VERTEBRAL FRACTURES AND RELATED FACTORS

Thanh Ngọc Cao 1,, Hoàng Hải Phạm 1
1 University of Medicine and Pharmacy at Ho Chi Minh City

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Abstract

Objective: This study aimed to investigate the diagnostic rate of osteoporosis in elderly patients with newly diagnosed vertebral fractures and related factors at the University Medical Center, Ho Chi Minh City. Methods: This cross-sectional study involved 227 elderly patients (≥ 60 years old), including 195 females and 42 males at the Rheumatology and Neurosurgery Departments, the Rheumatology, Neurosurgery, and Geriatrics outpatient Clinics of the University Medical Center, Ho Chi Minh City from August 2022 to March 2023. The Genant semiquantitative technique was used to diagnose vertebral fractures based on X-rays of thoracic/lumbar spine in the anteroposterior (AP)/posteroanterior (PA) and lateral positions. Data including demographic information, medical history and clinical examination findings were obtained. The diagnostic rate of osteoporosis was determined based on the patients medical records, prescriptions, and medical history. Results: The diagnostic rate of osteoporosis prior to vertebral fractures was 14,10% (32/227 patients). However, this rate increased significantly to 79,49% after vertebral fractures in the remaining patients (155/195 patients). The proportion of male elderly patients who were diagnosed with osteoporosis before and after vertebral fractures was lower than that of female elderly patients (4,76% vs. 16,22% before vertebral fractures; 70,00% vs. 87,74% after vertebral fractures). Multivariate logistic regression analysis revealed that educational attainment of high school or above (OR = 6,05, p < 0,001) and a history of fragility fractures (OR = 5,07, p = 0,002) were positively associated with the outcome of osteoporosis diagnosis before vertebral fractures. Conclusion: The proportion of elderly patients diagnosed with osteoporosis prior to vertebral fractures remained low. Furthermore, there were still patients who remain undiagnosed for osteoporosis even after vertebral fractures. Elderly patients with a high school education or above and a history of fragility fractures were more likely to be diagnosed with osteoporosis before vertebral fractures.

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References

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