KHẢO SÁT THỰC TRẠNG PHÂN LẬP VI KHUẨN VÀ MỨC ĐỘ NHẠY CẢM CỦA VI KHUẨN VỚI KHÁNG SINH TẠI BỆNH VIỆN QUẬN 2 – THÀNH PHỐ HỒ CHÍ MINH NĂM 2020

Abstract

Background and objectives: Determining the level of bacterial resistance at hospitals can help to choose antibiotics more effectively in treatment, while saving on antibiotic costs. This demonstrates the need to survey the current status of bacterial isolation and the sensitivity of bacteria to antibiotics in hospitals. Study population and methods: Bacterial strains isolated at District 2 Hospital, Ho Chi Minh City from January to December 2020 were studied using cross-sectional descriptive method. Results: 14 strains of Gram-negative bacteria and 8 strains of Gram-positive bacteria were isolated from 653 samples mainly from six clinical departments, including E. Coli 22.2%; Staphylococcus aureus 20.8%; Acinetobacter spp 12.3%. E. Coli was resistant to ampicillin (100%); nalidixic acid (91.5%); bactrim (92.7%); cefuroxime (75%); cefotaxime and ceftriaxone (72%), ciprofloxacin (72.7%). Acinetobacter spp showed high resistance to some third and fourth generation cephalosporins; imipenem (70.9%); gentamycin (75%). Staphylococcus aureus had high resistance to most antibiotics: penicillin (100%); erythromycin (93.4%); clindamycin (92.9%); azithromycin (91.9%); Bactrim (87.3%). Conclusion: Common bacteria isolated in the hospital include E. Coli, Staphylococcus aureus, and Acinetobacter spp. The isolated bacteria showed resistance to many commonly used antibiotics at different rates. Gram-negative Acinetobacter bacteria showed high resistance to imipenem. Gram-positive bacteria strains resistant to vancomycin and linezolid were also found.