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Date Published: 26/05/2023
Abstract Views: 878
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DOI: https://doi.org/10.51298/vmj.v526i1B.5423
Issue
Vol. 526 No. 1B (2023)
Section
Các bài báo
How to Cite
Lại , T. N. A. ., Ngô , T. M. B. ., Nguyễn, T. Q. ., Trần, H. Y. ., & Ngọc , T. D. . (2023). EVALUATION OF ACUTE TOXICITY AND SUB-CHRONIC TOXICITY OF HOANG LIEN SON NATURAL BUG EXTRACT. Vietnam Medical Journal, 526(1B). https://doi.org/10.51298/vmj.v526i1B.5423

EVALUATION OF ACUTE TOXICITY AND SUB-CHRONIC TOXICITY OF HOANG LIEN SON NATURAL BUG EXTRACT

Thị Ngọc Anh Lại 1,, Thị Mỹ Bình Ngô 1, Thu Quỳnh Nguyễn1, Hải Yến Trần1, Thanh Dũng Ngọc 2
1 Thai Nguyen University Of Medicine And Pharmacy
2 HaGiang Sub-department of Food Hygiene and Safety

Main Article Content

Abstract

Conducted research to evaluate acute toxicity and sub-chronic toxicity of Hoang Lien Son natural bug extract (ĐTBX) on mice and rat in the laboratory, showed that white mice drank powdery mildew liquid with different dose levels from 30,0 g/kg to 67,5 g/kg, no abnormal symptoms were observed in mice, nor did any mice die. White rat drinking ĐTBX dose of 0,42 g/kg/day and dose of 1,26 g/kg/day, continuously for 90 days, did not affect the general condition, body weight of rats as well as blood indices, histopathology, biochemical indices and histopathology of liver, spleen and kidney. From the above results, we conclude that Hoang Lien Son natural bug extract is safe in acute toxicity and sub-chronic toxicity tests on experimental animals.

Article Details

Keywords

Hoang Lien Son natural bugs, acute toxicity, sub-chronic toxicity

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