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Date Published: 26/05/2023
Abstract Views: 150
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DOI: https://doi.org/10.51298/vmj.v526i1B.5435
Issue
Vol. 526 No. 1B (2023)
Section
Các bài báo
How to Cite
Nguyễn, M. C., Trần, T. K. M. ., Ngô , Đức H. ., Đinh , T. L. A. ., Nguyễn, L. A. ., & Hà, T. H. . (2023). CORRELATION BETWEEN THROMBOELASTOMETRY (ROTEM) AND ROUTINE COAGULATION TESTS IN PATIENTS WITH ACUTE LIVER FAILURE. Vietnam Medical Journal, 526(1B). https://doi.org/10.51298/vmj.v526i1B.5435

CORRELATION BETWEEN THROMBOELASTOMETRY (ROTEM) AND ROUTINE COAGULATION TESTS IN PATIENTS WITH ACUTE LIVER FAILURE

Mạnh Chiến Nguyễn1,2,, Thị Kiều My Trần1,3, Đức Hùng Ngô 1, Thị Lan Anh Đinh 1, Long An Nguyễn2, Trần Hưng Hà1,2
1 Hanoi medical university
2 ICU
3 NATIONAL INSTITUTE OF HEMATOLOGY AND BLOOD TRANSFUSION

Main Article Content

Abstract

Objective: to assess the correlation between Rotational thromboelastometry (ROTEM) and routine coagulation tests in patients with acute liver failure. Subjects and methods: observational study included 52 patients with acute liver failure treated at Poison Control Center of Bach Mai hospital from 8/2018 to 7/2019. Results: All patients had decreased prothrombin, most had a severe decrease (63.5%). Most of study patients had prolonged APTTs (86.5%), decreased fibrinogen (69.2%). There was a high correlation between APTTs and CT INTEM (r = 0.622, p < 0.001) because in acute liver failure, coagulation factors are reduced leading to decreased activation of coagulation. However, CT EXTEM and PT% had a low correlation (r= -0.377, p=0.006) and the maximal clot amplitude in FIBTEM was moderately correlated with fibrinogen. Conclusion: The study showed a heterogeneous correlation between ROTEM and routine coagulation tests in patients with acute liver failure.

Article Details

Keywords

ROTEM, acute liver failure, routine coagulation tests

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