CYTOTOXICITY OF CALCIUM SILICATE - BASED ROOT CANAL SEALER ON HUMAN PERIODONTAL LIGAMENT STEM CELLS

Thị Quỳnh Mai Lâm 1, Phạm Thùy Nhung Trần2, Xuân Vĩnh Trần1,
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 National Hospital of Odonto-Stomatology, HCM city

Main Article Content

Abstract

Objective: This study was designed to evaluate the cytotoxicity of calcium silicate root canal sealer (BioRoot RCS; Septodont, Saint Maur Des Fossés, France) and calcium silicate root canal sealer CeraSeal (Meta-Biomed, Korea). Methods: Human periodontal ligament stem cells were exposed to direct extraits of different concentrations of each material. The percentage of survival cell (%) was then determined using the MTT assay. Results: Safe concentrations (percentage of survival cell > 70%) of BioRootTM RCS is from 50% onwards, CeraSeal is safe at all concentrations. Conclusion: BioRootTM RCS and CeraSeal are two root canal sealers that have less cytotoxicity on human periodontal ligament stem cells.

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References

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