NHIỄM KHUẨN BỆNH VIỆN TẠI TRUNG TÂM HỒI SỨC TÍCH CỰC NGƯỜI BỆNH COVID-19 TRỰC THUỘC BỆNH VIỆN BẠCH MAI – TP. HỒ CHÍ MINH NĂM 2021

Abstract

Objectives: The study aimed to determine the rate of hospital-acquired infections, pathogens, risk factors and treatment outcomes related to hospital-acquired infections at the Intensive Care Unit for COVID-19 patients under Bach Mai Hospital - Ho Chi Minh City. Ho Chi Minh in 2021. Method: This was a retrospective analysis of prospectively collected data of all consecutive patients with COVID-19 hospitalized for treatment at the Intensive Care Center for COVID-19 patients under Bach Mai Hospital - Ho Chi Minh City from August 11 to October 30, 2021. Results: Among 1,137 sampled patients, 318 demonstrated 411 HAIs (28%). Pneumonia (n= 294 [71,5%]) and bloodstream infections (n = 74 [18,0%]) were the most common HAIs. Multidrug-resistant (MDR) bacteria such as Acinetobacter baumannii (31,9%) and Klebsiella pneumonia (25,7%) and were the most common isolated organisms. Diabetes (OR=1.7; CI95%: 1.2 – 2.4; p < 0.05); Cardiovascular disease (OR=1.8; CI95%: 1.3 – 2.6; p < 0.05); Interventional procedures: CPAP (OR=3.3; CI95%: 2.4 – 4.7; p < 0.001); Intrusive ventilator (OR=2.6; CI95%: 1.3 – 5.1; p < 0.001); Central venous catheter (OR=2.5; CI95%: 1.7 – 3.6; p < 0.05); Indwelling urinary catheter (OR=4.01; CI95%: 1.7 – 9.5; p < 0.05) were independently associated with HAIs. Conclusions: The rate of patients with NKBV is 28%. Pneumonia and bloodstream infections are the two most common types of hospital-acquired infections in patients with COVID-19. Most of the pathogens that cause UTIs isolated were Gram-negative bacteria Acinetobacter baumannii and multi-antibiotic resistant Klebsiella pneumonia. The study results also showed that the factors related to BV include invasive mechanical ventilation, CPAP breathing, catheterization. central vein, bladder catheterization, diabetes mellitus, cardiovascular disease on admission.