A STUDY APPLICATION OF xSPECT IMAGE PROCESSING TECHNOLOGY IN SPECT/CT RECORDING

Tuấn Long Nguyễn1,, Thành Công Phạm 1, Xuân Ngọc Lê2
1 Hanoi University of Science and Technology
2 Oncology Hospital (Thanh Hoa)

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Abstract

Objectives of the study: Application of xSPECT image processing technology in SPECT/CT radiographic imaging. Subjects and methods: SPECT/CT of Siemens, Germany. xSPECT software; Phan-tom water; SPECT/CT bone scan with 99mTc-MDP in patients with prostate carcinoma. Results: Results using four reconstruction methods: xSPECT Quant (xQ); xSPECT Bone™ (xB); Flash 3D (F3D); OSEM, shows that the system matrix modeling is more accurate than the updated schema. Quantitative results of background and 6 spheres using xE, xQ and xB with 3 degree and 6 degree angle sampling after many updates, all methods give very accurate estimates (nearly 100 %) to the background and the results are stable with updates. Bone scintigraphy in 40 prostate cancer patients by SPECT/CT with 99mTc-MDP detected 50 lesions, of which: SPECT 60% (30/50) was said to be unclear, when use of XSPECT with SPECT/CT clarified the diagnosis in 52% of suspected lesions only 8% (4/50) remained unclear.

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References

1. Nguyễn Danh Thanh, Nguyễn Kim Lưu (2016), Y học hạt nhân: Chẩn đoán và điều trị, Giáo trình sau đại học, Học viện Quân y.
2. I. Duncan and N. Ingold (2018), "The clinical value of xSPECT/CT Bone versus SPECT/CT. A prospective comparison of 200 scans", Eur J Hybrid Imaging. 2(1), p. 4.
3. O. Delcroix, et al. (2018), "A new SPECT/CT reconstruction algorithm: reliability and accuracy in clinical routine for non-oncologic bone diseases", EJNMMI Res. 8(1), p. 14.
4. H. Ichikawa, et al. (2022), "Feasibility of ultra-high-speed acquisition in xSPECT bone algorithm: a phantom study with advanced bone SPECT-specific phantom", Ann Nucl Med. 36(2), pp. 183-190.
5. B. Iqbal, et al. (2011), "The incremental value of SPECT/CT in characterizing solitary spine lesions", J Nucl Med Technol. 39(3), pp. 201-7.
6. L. Jiang, et al. (2013), "Diagnostic value of ⁹⁹mTc-MDP SPECT/spiral CT in assessing indeterminate spinal solitary lesion of patients without malignant history", Ann Nucl Med. 27(5), pp. 460-7.