MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG UNG THƯ DẠ DÀY TẾ BÀO NHẪN

Abstract

Aims: To review some relevant clinically and paraclinically features for signet-ring cell gastric cancer. Patients and Methods: 71 patients with signet-ring cell gastric cancer who were experiended radical gastrectomy at Vietnam National Cancer hospital. Method: Prospective cohort combines retrospective cohort. Results: The average age of disease: 54,5±9,7. History of gastritis 31%. 9.9% of patients have relatives who have gastric cancer. Epigastric abdominal pain (94.4%); gastrointestinal bleeding (7.0%); pyloric stenosis (7.0%). 40.8% fragility. Tumor position: upper-third(5.6%); middle-third(31.0%); lower-third (60.6%). Morphology according to Borrman: type 1 (52,1%); type 2 (25,6%); type 3 (21,1%) and type 4 (4,2%). Signet ring cell carcinoma  was more likely to be stage T3, T4 (19,7% and 71.8%), have lympho node spread (45,1%). 33.8% of patients had an increase tumor markers in preoperative. 19.7 % of preoperative diagnosis is non-signet ring cell gastric cancer. Conclusion: Signet-ring cell carcinoma has the characteristics of clinical and subclinical differences. This will help clinicians to have more appropriate approaches and treatment strategies for this disease.