EFFECT OF TEMPERATURE, CONCENTRATION AND WAVELENGTH OF LIGHT ON THE SPECIFIC ROTATION OF OPTICAL ACTIVE SOLUTION

Thị Hồng Đức Nguyễn1,, Đức Thiện Nguyễn1, Uyển Hương Mai 1
1 Hanoi University of Pharmacy

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Abstract

The specific rotations of active pharmaceutical ingredients are characterized by their ability of light to rotate the polarization plane of the light. The improved P1000 mechanical polarization experiment uses LEDs with 4 primary colors with a polarizer tube 1 dm long and has a temperature probe attached to investigate. The results showed that the specific polar rotation of the solution depends on the molecular structure, temperature, solution concentration and the light wavelength. The angle of rotation of the plane of polarized light is linearly dependent on the concentration of the sugar solution, reaching the largest value when using blue light and the smallest using red light. Beside that we noticed the brown sugar due to the additional component magnesium and potassium has more ability to rotate the polarized light than the white one. Final, these findings provide an understanding of the properties of polarized light passing through a photoactive solution, which has great implications for medical and pharmaceutical research.

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References

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