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Date Published: 01/06/2023
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DOI: https://doi.org/10.51298/vmj.v526i2.5565
Issue
Vol. 526 No. 2 (2023)
Section
Các bài báo
How to Cite
Nguyễn, T. H. Đức ., Nguyễn, Đức T. ., & Mai , U. H. (2023). EFFECT OF TEMPERATURE, CONCENTRATION AND WAVELENGTH OF LIGHT ON THE SPECIFIC ROTATION OF OPTICAL ACTIVE SOLUTION. Vietnam Medical Journal, 526(2). https://doi.org/10.51298/vmj.v526i2.5565

EFFECT OF TEMPERATURE, CONCENTRATION AND WAVELENGTH OF LIGHT ON THE SPECIFIC ROTATION OF OPTICAL ACTIVE SOLUTION

Thị Hồng Đức Nguyễn1,, Đức Thiện Nguyễn1, Uyển Hương Mai 1
1 Hanoi University of Pharmacy

Main Article Content

Abstract

The specific rotations of active pharmaceutical ingredients are characterized by their ability of light to rotate the polarization plane of the light. The improved P1000 mechanical polarization experiment uses LEDs with 4 primary colors with a polarizer tube 1 dm long and has a temperature probe attached to investigate. The results showed that the specific polar rotation of the solution depends on the molecular structure, temperature, solution concentration and the light wavelength. The angle of rotation of the plane of polarized light is linearly dependent on the concentration of the sugar solution, reaching the largest value when using blue light and the smallest using red light. Beside that we noticed the brown sugar due to the additional component magnesium and potassium has more ability to rotate the polarized light than the white one. Final, these findings provide an understanding of the properties of polarized light passing through a photoactive solution, which has great implications for medical and pharmaceutical research.

Article Details

Keywords

Specific rotation, optical activity, white sugar, brown sugar, wavelength, temperature, sugar concentration.

References

1. Vos M. B. et al (2017), “Added Sugars and Cardiovascular Disease Risk in Children: A Scientific Statement From the American Heart Association,” Circulation, 135(19)
2. Soni M. (2019), “A Review on the Measurement of Optical Activity by Using a Polarimeter,” J. Pharmacogn. Phytochem., 8(2), pp. 358–360.
3. Matti D. J. (2014), “Study the Effect of the Sugar Solutions on the Rotation of the Plane of Polarization,” Nahrain Univ. Coll. Eng. J., Vol.17(No.1), pp. 60–66.
4. Anderson J., Gillen C., et al. (2020), “Optical Rotation of White Light,” Am. J. Phys., 88(3), p. 247.
5. “European Pharmacopoeia 10.1 V.1-2. Strasbourg: Council of Europe,” 2021”
6. “Japanese Pharmacopoeia 18th Edition - English Version Now Available - ECA Academy,2021”
7. Kvittingen L., and Sjursnes B. J. (2020), “Demonstrating Basic Properties and Application of Polarimetry Using a Self-Constructed Polarimeter,” J. Chem. Educ., 97(8), pp. 2196–2202.
8. Nardone E., Dey T., et al. (2013), “The Effect of Sugar Solution Type, Sugar Concentration and Viscosity on the Imbibition and Energy Intake Rate of Bumblebees,” J. Insect Physiol., 59(9), pp. 919–933.