COMBINATION OF BACTERIA, VIRUS IN HOSPITALIZED COMMUNITY - ACQUIRED PNEUMONIA PATIENTS
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Abstract
Background: Hospitalized community - acquired pneumonia (CAP) is a common disease that can be caused by one or more bacteria and virus in pathogenic combination. The multiplex real-time PCR is used as an optimal technique with high sensitivity and specificity to detect pathogenic agents, especially agent combination. Objects: To determine the rate of bacterial and viral combination in hospiatalized community - acquired pneumonia patients and the relationship between the combination with patient’s age and gender. Methods: Subjects were 138 samples of the sputum from CAP patients hospitalized at Nguyen Tri Phuong hospital. Before using the multiplex real-time PCR to detect pathogenic agents, these sputums were assessed for the reliability based on Barlett’s scale. Results: There were 136 cases (98.6%) detected bacterial and viral pathogens, in which the single agents were 15 cases (11.0%) with 7 cases of single bacteria (5.1%) and 8 cases of single virus (5.9%), the multiple agents were 121 cases (89.0%). The rate of combination between bacterial agents was 14.7%, between viral agents was 4.4% and between bacterial and viral agents was 69.9%. There was no statistically significant relationship between the ratio of the pathogenic agent combination with the age group and with the gender of patients (p > 0.05). Conclusions: The rate of combination between bacterial agents is 14.7%, between viral agents is 4.4% and between bacterial and viral agent is 69.9%. There is no statistically significant relationship between the ratio of the pathogenic agent combination with the age group and with the gender of patients (p > 0.05).
Article Details
Keywords
Hospitalized community - acquired pneumonia, combination of bacterial and viral agent.
References
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