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Date Published: 24/07/2021
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DOI: https://doi.org/10.51298/vmj.v502i1.560
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Vol. 502 No. 1 (2021)
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Văn Chủ, N. ., Lê Giang, T. ., & Thanh Phương, V. . (2021). ASSESSMENT OF LYMPH NODE STATUS AND SOME PROGNOSTIC HISTOPATHOLOGICAL FACTORS OF MALIGNANT MELANOMA. Vietnam Medical Journal, 502(1). https://doi.org/10.51298/vmj.v502i1.560

ASSESSMENT OF LYMPH NODE STATUS AND SOME PROGNOSTIC HISTOPATHOLOGICAL FACTORS OF MALIGNANT MELANOMA

Nguyễn Văn Chủ, Trần Lê Giang, Vũ Thanh Phương

Main Article Content

Abstract

Assessment of the lymph node status of malignant melanoma remains the standard of treatment. Histopathological type and features can provide the prognostic information. Purpose: Comment on the relationship between some histopathological features with the lymph node status of melanoma. Methods: 121 melanoma patients were assessed for lymph node status, histopathological subtype and some pathological features. Results: The rate of the metastasized lymph node groups were increased with Clark degrees, especially to the 2-3 node, Clark V was accounted for the highest rate of 78.6%, followed by the  positive 1 node group, Clark V was 69.6 % and ≥4 lymph node group was 55.0% (p <0.05). In 2-3 or ≥4 metastasized lymph node groups, melanoma without lymphocyte infiltration showed the highest proportion (17.7 and 21.6%, respectively) (p < 0.05). Conclusion: The lymph node status of malignant melanoma is strongly related to Clark degree and tumor lymphocytic infiltration.

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Keywords

Malignant melanoma, Lymph node status, Histopathological characteristic

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