NHẬN XÉT MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG VÀ CẬN LÂM SÀNG UNG THƯ LƯỠI DI ĐỘNG Ở BỆNH NHÂN TRẺ TUỔI TẠI BỆNH VIỆN K

Abstract

Objectives: To evaluate the clinical and subclinical characteristics of young patients with squamous cell carcinoma oral tongue cancer at K hospital. Patients and methods: A retrospective and prospective descriptive study was conducted on 46 young patients (≤40 years old) with squamous cell carcinoma oral tongue cancer treated at K hospital from January 2017 to May 2022. Results: The mean age was 34.09; male/female ratio was 0.84/1. The reason that patients were admitted to hospital were pain (63%) and detection of tumor (30.4%). 58.7% of patients went to hospital within 3 months from the first symptoms. The first signs and symptoms were pain (60.9%), detection of tumor (26.1%) and tongue ulcer (13%). The most common location of tumor was tongue edge (89.1%). The most morphological subtype was nodular-ulcerative (41.3%). On T1 MRI, 67.4% of patients had hypointense lesion and 95.7% of tumors had increased signal after injection; On STIR MRI, most of the tumors were hyperintense signal (95.7%). About pathology, the majority of patients are moderately differentiated (78,3%). Conclusions:  Mobile tongue cancer in young adults (≤40 years) was uncommon. Most patients were admitted to the hospital at an earlier stage when symptoms appear in the first 3 months with a common location in tongue edge. Magnetic resonance imaging played an important role in the diagnosis of tongue cancer. Pathology remained the gold standard in diagnosis of mobile tongue cancer.