TÌM HIỂU NỒNG ĐỘ ACID URIC MÁU Ở BỆNH NHÂN SAU GHÉP THẬN TẠI BỆNH VIỆN BẠCH MAI

Abstract

Objective: (1) Evaluation of serum acid uric (AU) level in renal transplantation patients at Bach Mai hospital. (2) Study of the relationship between serum acid uric level with some clinical and subclinical factors at this group patient. Subjects and Methods: a cross-sectional descriptive of 346 patients after kidney transplantation at the outpatient kidney transplant clinic- at Bach Mai Hospital from April 2022 to October 2022. Results: The percentage of hyperuricemia in 346 patients after kidney transplantation followed up at the Outpatient Kidney Transplant clinic- at Bach Mai Hospital was 49.4%. This ratio in woman is similar to men. The most common age group to increase serum AU level is 30 – 39 years old. The status of increased serum AU level was seen at a higher rate in the group with a time of 1-3 years after kidney transplant (62.5%, statistically significant difference compared with the transplant group less than 1 year or more than 3 years). The rate of increased serum AU level in the group with dyslipidemia and the group without ACE/ARB was statistically significantly higher than in the group without dyslipidemia and the ACE/ARB group respectively. The mean GFR in the group with hyperuricemia was statistically significantly lower than that in the group with normal serum AU levels (p < 0.05). Conclusion: Attention to assessment and treatment of hyperuricemia in patients after kidney transplantation is an important factor contributing to maintaining stable long-term kidney transplant function.