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Date Published: 27/06/2023
Abstract Views: 341
Views PDF: 216
DOI: https://doi.org/10.51298/vmj.v527i1B.5713
Issue
Vol. 527 No. 1B (2023)
Section
Các bài báo
How to Cite
Ngô , V. C. ., & Trương , M. T. . (2023). CLINICAL AND PARACLINICAL FEATURES IN PATIENTS WITH SEVERE DEEP NECK INFECTIONS AND DIABETES MELLITUS AT CHO RAY HOSPITAL. Vietnam Medical Journal, 527(1B). https://doi.org/10.51298/vmj.v527i1B.5713

CLINICAL AND PARACLINICAL FEATURES IN PATIENTS WITH SEVERE DEEP NECK INFECTIONS AND DIABETES MELLITUS AT CHO RAY HOSPITAL

Văn Công Ngô 1,, Minh Thịnh Trương 2
1 Cho Ray hospital
2 University of Medicine and Pharmacy at Ho Chi Minh City

Main Article Content

Abstract

Objective: To investigate clinical and subclinical characteristics in patients with severe deep neck infections with diabetes mellitus and compare the difference between this group with the nondiabetic group. Methods: We did a descriptive study on 100 cases of severe deep neck infections treated at Cho Ray Hospital from 12/2019 to 12/2022. Results: In patients with severe deep neck infections with diabetes mellitus: dental cause was the most common (21.3%); Streptococcus sp (39.3%) and Klebsiella pneumoniae (26.2%) were the most commonly isolated organisms; there was an increase in leukocytes (14.7 ± 6.3 G/L) and CRP (235.6 ± 111.8 mg/L) on admission; airway obstruction (49.2%) and mediastinitis (36.1%) were the most common complications. Compared with the nondiabetic group, the diabetic group had a higher mean age (59.6y versus 52.9y; p=0.02) and more frequently isolated Klebsiella pneumoniae (26.2% versus 7.7%; p=0.02). Conclusion: Initial antibiotic therapy should cover Streptococcus sp and Klebsiella pneumoniae in patients with severe deep neck infections with diabetes mellitus.

Article Details

Keywords

Deep neck infections, diabetes mellitus, clinical features, complications

References

1. Hidaka H, Yamaguchi T, Hasegawa J, et al. Clinical and bacteriological influence of diabetes mellitus on deep neck infection: Systematic review and meta-analysis. Head Neck. Oct 2015;37(10):1536-46. doi:10.1002/hed.23776
2. Huang TT, Tseng FY, Liu TC, Hsu CJ, Chen YS. Deep neck infection in diabetic patients: comparison of clinical picture and outcomes with nondiabetic patients. Otolaryngol Head Neck Surg. Jun 2005;132(6):943-7. doi:10.1016/j.otohns.2005.01.035
3. Zheng L, Yang C, Kim E, et al. The clinical features of severe multi-space infections of the head and neck in patients with diabetes mellitus compared to non-diabetic patients. Br J Oral Maxillofac Surg. Dec 2012;50(8):757-61. doi:10.1016/j.bjoms.2012.01.019
4. Huỳnh Dao, Trần Anh Bích, et al. Khảo sát lâm sàng và đánh giá kết quả điều trị nhiễm trùng cổ sâu trên bệnh nhân đái tháo đường tại khoa Tai Mũi Họng Bệnh viện Chợ Rẫy từ tháng 9/2020 đến 6/2021. Y Học Thành Phố Hồ Chí Minh. 2022;26(1/2022)
5. Trần Anh Bích, Trần Minh Trường. Nhiễm trùng cổ sâu trên bệnh nhân đái tháo đường: so sánh hình ảnh lâm sàng và kết quả điều trị với bệnh nhân không đái tháo đường từ 1/2005 đến 9/2006. Tạp chí Y học thành phố Hồ Chí Minh. 2006;11(1)
6. Wang LF, Tai CF, Kuo WR, Chien CY. Predisposing factors of complicated deep neck infections: 12-year experience at a single institution. J Otolaryngol Head Neck Surg. Aug 2010;39(4):335-41.
7. Luan CW, Liu CY, Yang YH, et al. The Pathogenic Bacteria of Deep Neck Infection in Patients with Type 1 Diabetes, Type 2 Diabetes, and Without Diabetes from Chang Gung Research Database. Microorganisms. Sep 29 2021;9(10)doi:10.3390/microorganisms9102059