MOTOR CHARACTERISTICS OF YOUNG-ONSET PARKINSON PATIENTS: STUDY OF 100 CASES

Thị Thúy An Lê1,, Trúc Dung Nguyễn1, Thanh Tú Trần2, Thi Hùng Nguyễn3
1 University of Medicine and Pharmacy at Ho Chi Minh City
2 Cho Ray hospital
3 Hai Phong University Of Medicine And Pharmacy

Main Article Content

Abstract

Objective: To indentify the severity of young onset Parkinson's disease by using the MDS-UPDRS part III and determine the correlation between MDS-UPDRS score and Hoehn - Yahr staging. Subjects and methods: A descriptive cross-sectional study was conducted on 100 patients diagnosed with Parkinson's disease under 50 years old, all these patients attended the neurology clinic at Cho Ray hospital from July 2020 to July 2022 were interviewed and clinically examined by movement disease specialist based on prepared questionnaire, the all data was statistically analyzed by biostatistic expert. Result: The median score of movement disorders from the MDS-UPDRS part III was 35,5 and the interquartile range was 25,5 – 47,5. There was a weak positive correlation between MDS-UPDRS part III score with age, duration of disease but a strong positive correlation between Hoehn and Yahr classification with MDS-UPDRS score part III (p<0,05). There was a relationship significantly between the time of exposure to pesticides and herbicides with the MDS-UPDRS score part III (p<0,05). Conclusion: A survey on 100 young onset Parkinson disease patients noticed that there is a statistically correlation between the severity of MDS-UPDRS part III and the duration of diseases. Regarding patients exposed to insecticide and herbicides, we noticed a significantly relationship with the severity of MDS-UPDRS part III.

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References

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