CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH CHRONIC INDUCIBLE URTICARIA

Thị Hồng Hạnh Ngô1, Văn Đức Lê1, Huyền My Lê2, Hữu Doanh Lê1,2, Hải Yến Vũ2, Nguyệt Minh Vũ1,2,
1 HMU
2 National Hospital of Dermatology and Venereology

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Abstract

Objectives: To study patients' clinical features and common laboratory characteristics with chronic inducible urticaria (chronic inducible urticaria-CIndU). Subjects and methods: This was a cross-sectional descriptive study based on data from 142 patients with a confirmed diagnosis of CIndU, who visited the National Hospital of Dermatology and Venereology (NHDV) from July 2021 to July 2022. Results: A total of 142 patients were identified. Symptomatic dermographism (SD) was the most common form, accounting for 46.5% (n=66), followed by choline urticaria (n=55, 38.7%) and cold urticaria (n=18, 12.7%), respectively. Other forms of CIndU such as delayed pressure urticaria, vibratory urticaria,... accounted for 2.1% (n=3). 25.4% of patients had associated chronic spontaneous urticaria (chronic spontaneous urticaria-CSU). CIndU equally affected men and women with p>0,05. The most common age of onset was in the 2nd and 3rd decade, accounting for 45.8% of cases. 64.8% of patients reported a severe impact on their quality of life (Dermatology Life Quality Index-DLQI>10). The mean values of all laboratory parameters were within the normal range. Conclusion: SD was the most common form of CIndU, followed by choline urticaria and cold urticaria. The disease had an early onset at a relatively young age and often associated with CSU. CIndU seriously affects the quality of life of patients.

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References

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