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EFFECT OF METABOLIC SYNDROME ON LEFT VENTRICULAR FUNCTION IN PATIENTS WITH TYPE 2 DIABETES
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Abstract
Objectives: To determine the effect of metabolic syndrome (MS) on residual function of left ventricular in patients with type 2 diabetes mellitus. Subjects and research methods: A cross-sectional descriptive study was conducted with 183 type 2 diabetes patients with MS and 75 type 2 diabetes patients without MS at Thai Binh Medical University Hospital from February to August 2022. All of patients were evaluted left ventricular function by echocardiography. Research results: The average age of patients was 69.3 ± 7.8 years (Female/Male with MS = 2/1), the highest prevalence (74%) occurs in the 60 to 69 years age group with MS. The isovolemic contraction time (IVCT), isovolemic relaxation time (IVRT), Tei index in the group with MS were significantly greater than the group without MS (94.8 ± 38 versus 77.5 ± 40.2 (ms), p < 0.05; 116.5 ± 32.1 versus 94.4 ± 39.9 (ms), p < 0.001; 0.81 ± 0.35 versus 0.64 ± 0.20, p < 0.05, respectively). The E wave velocity and the E/A ratio in the group with MS were smaller than the group without MS (48.8 ± 19.1 versus 54.4 ± 18.0, p < 0,05 and 0.66 ± 0.42 versus 0.79 ± 0.32; p < 0.05, respectively). The A wave velocity in the group with MS was larger than the group without MS (77.4 ± 21.5 versus 70.8 ± 18.3, p < 0,05, respectively). There was no differences in contraction fraction (%D), ejection fraction (EF%), stroke volume (SV) and cardiac output (CO) between two groups. Conclusion: Factors of metabolic syndrome reduce diastolic function and total left ventricular function but do not affect left ventricular systolic function in patients with type 2 diabetes
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Keywords
Type 2 diabetes mellitus (DM), metabolic syndrome (MS), left ventricular function
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