RISK FACTORS FOR AB INTERNO TRABECULOTOMY IN TREATING PRIMARY OPEN-ANGLE GLAUCOMA

Tấn Đỗ1,, Thị Vân Anh Bùi1, Thái Đạt Nguyễn1
1 VIETNAM NATIONAL INSTITUTE OF OPHTHALMOLOGY

Main Article Content

Abstract

Objective: Evaluating the risk factors for ab interno trabeculotomy using iTrack microcatheter in treating primary open-angle glaucoma with prior failed incisional glaucoma surgery. Subjects and methods: This is a prospective clinical interventional study without control group. The studied subjects were 15 eyes (14 patients) diagnosed with open-angle glaucoma at the Glaucoma Department, Vietnam National Eye Hospital from March 2022 to December 2022. Selection criteria included: primary open-angle glaucoma eyes with prior failed incisional glaucoma surgery even using ≥ 2 different hypotensive drugs. All patients were older than ≥ 18 years old. Gender, age, past surgical history, preoperative visual acuity, preoperative intraocular pressure, axial length, complication, the extent of opned Schlemm canal during surgery and other factors were analysed using medical statistical algorithms. Results: The mean extent of the opened Schlemm’s canal during surgery in eyes with surgical success was higher than that in eyes with surgical failure (249,1°± 55,39° versus 147,5°±39,47°). The failure rate in eyes with postoperative hyphema greater than or equal to grade 1 after surgery was 75% while the failure rate in eyes with grade 0 hyphema was 9,1%. There was no correlation between factors such as age, gender, preoperative visual acuity, preoperative intraocular pressure, etc and the surgical outcomes. Conclusion: The extent of the opened Schlemm’s canal during ab interno trabeculotomy and the postoperative degree of hyphema were the 2 factors which affected significantly the surgical outcomes. Greater degree of Schlemm canal opened led to higher success rate and lower postoperative intraocular pressure. The grade of postoperative hyphema greater or equal to greater than grade 1 increased the probability of surgical failure.

Article Details

References

1. Grover DS, Godfrey DG, Smith O, Feuer WJ, Montes de Oca I, Fellman RL. Gonioscopy-assisted transluminal trabeculotomy, ab interno trabeculotomy: technique report and preliminary results. Ophthalmology. Apr 2014;121(4):855-61. doi:10.1016/j.ophtha.2013.11.001
2. Grover DS, Godfrey DG, Smith O, Shi W, Feuer WJ, Fellman RL. Outcomes of Gonioscopy-assisted Transluminal Trabeculotomy (GATT) in Eyes With Prior Incisional Glaucoma Surgery. J Glaucoma. Jan 2017;26(1):41-45. doi:10.1097/IJG.0000000000000564
3. Johnson DH, Matsumoto Y. Schlemm's canal becomes smaller after successful filtration surgery. Arch Ophthalmol. Sep 2000;118(9):1251-6. doi:10.1001/archopht.118.9.1251
4. Sato T, Kawaji T, Hirata A, Mizoguchi T. 360-degree suture trabeculotomy ab interno to treat open-angle glaucoma: 2-year outcomes. Clin Ophthalmol. 2018;12:915-923. doi:10.2147/OPTH.S161238
5. Chin S, Nitta T, Shinmei Y, et al. Reduction of intraocular pressure using a modified 360-degree suture trabeculotomy technique in primary and secondary open-angle glaucoma: a pilot study. J Glaucoma. Aug 2012;21(6):401-7. doi:10.1097/IJG.0b013e318218240c
6. Faria BM, Daga FB, Reboucas-Santos V, et al. Gonioscopy-assisted transluminal trabeculotomy (GATT) outcomes in eyes with open-angle glaucoma resistant to maximum treatment. Arq Bras Oftalmol. Nov-Dec 2021; 84(6):587-593. doi:10.5935/0004-2749.20210083
7. Bektas C, Aktas Z, Ucgul AY, Karamert SS. Prognostic factors affecting the surgical success of gonioscopy-assisted transluminal trabeculotomy. Indian J Ophthalmol. Jun 2021;69(6):1425-1429. doi:10.4103/ijo.IJO_2035_20