ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG CỦA BỆNH THALASSEMIA Ở TRẺ EM ĐIỀU TRỊ TẠI BỆNH VIỆN TRUNG ƯƠNG THÁI NGUYÊN

Abstract

The aims were to describe the clinical, subclinical characteristics and review some characteristics after blood transfusion of thalassemia pediatric patients in Thai Nguyen National Hospital. Methods: A cross-sectional study was performed on 53 pediatric patients with thalassemia treated at the Clinical Hematology Department, Thai Nguyen Central Hospital from 1/2022 to 1/2023. Results: The female rate (56,6%) was higher than male rate; the majority of patients are ethnic minorities (81.1%); the age group 6-10 accounted for the highest percentage (56,6%), the mean age was 7,9 ± 0,83. Common clinical symptoms were: melasma (69,8%), jaundice (73,6%), hepatomegaly (86.8%), splenomegaly accounting for 56.6% and 20/53 patients had splenectomy (37.7%). The test showed that: mean RBC was 3,06 ± 1,02 T/l, mean Hb was low (mean Hb 69,13± 23,66g/l), mean ferritin was high (1436,07 ± 369,24). After blood transfusion treatment, the red blood cells, hemoglobin and ferritin in the blood of pediatric patients all increased, this difference was statistically significant with p<0.05.