KHẢO SÁT MẬT ĐỘ XƯƠNG VÀ CÁC YẾU TỐ LIÊN QUAN Ở BỆNH NHÂN SUY THẬN MẠN TẠI BỆNH VIỆN 19-8

Abstract

Objective: Describe the bone density characteristics of patients with stage 3-5 chronic kidney disease (CKD) and end-stage renal disease (ESRD) undergoing hemodialysis at 19-8 Hospital.Study Population and Methods: A cross-sectional descriptive study was conducted on 152 CKD patients, divided into two groups: 93 CKD patients in stages 3-5 who had not received renal replacement therapy, and 59 ESRD patients undergoing cyclical hemodialysis at 19-8 Hospital. Blood samples were collected from all patients for laboratory testing, and bone density measurements were taken at the lumbar spine, femoral neck, and total hip using Dual-Energy X-ray Absorptiometry (DEXA) method. Results: In the group of 93 CKD patients in stages 3-5 (female: 22.6%, male: 77.4%), the mean age was 67.71±15.0344 years. The average bone density measurements were as follows: lumbar spine (1.0939±0.213 g/cm2), total hip (0.8591±0.256 g/cm2), and femoral neck (0.7679±0.166 g/cm2). The prevalence of osteoporosis was 31.2%, and the proportion of decreased bone density was 39.8%. In the group of 59 ESRD patients undergoing cyclical hemodialysis (female: 33.9%, male: 66.1%), the mean age was 52±14.1446 years. The average bone density measurements were as follows: lumbar spine (1.072±0.167 g/cm2), total hip (0.8178±0.131g/cm3), and femoral neck (0.7457±0.127 g/cm3). The prevalence of osteoporosis was 28.8%, and the proportion of decreased bone density was 50.8%.