CLINICAL AND LABORATORY CHARACTERISTICS OF PATIENTS WITH DRUGS OF ABUSE POISONING AT POISON CONTROL CENTER BACHMAI HOSPITAL

Đặng Thị Xuân, Nguyễn Trung Anh

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Abstract

Objective: to assess clinical and laboratory characteristics of patients with  non-opium drugs of abuse poisoning. Subjects and Methods: A observational study included 72 poisoned non-opium drug poisoning patientstreated at Poison Control Center Bach Mai Hospital from 1/2017 to 6/2019. Results: Common non-opium drugs of abuse: Amphetamine (29.2%), MET (22.2%), MDMA (19.4%), THC (20.8%), Ketamin (8.3%). The main clinical features of cardiovascular and central nervous system in sympathomimetic and serotonin syndromes: tachycardia (73.6%), increased blood pressure (45.8%), fever (43.1%); Consciousness disorder 100% (stimulus 58.3%, struggling 23.6% and 18.1% confusion/coma), increased sweating (77.8%), dilated pupils (59.7%), increased muscle tone (55.6%), increased tendon reflexes (47.2%); 84.7% have serotonin syndrome. Laboratory: leukocytosis (41.7%), increased CK(38.9%), rhabdomyolysis (13.9%), ​​acute renal failure (12.5%), increased troproninT (10%). Conclusion: the evaluation of clinical and laboratory characteristics in patients with drugsof abuse poisoning is essential for early diagnosis and management of patients.

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