KHẢO SÁT NGUYÊN NHÂN VIÊM TỤY CẤP VÀ MỐI LIÊN QUAN VỚI MỨC ĐỘ NẶNG CỦA BỆNH TẠI TRUNG TÂM TIÊU HÓA GAN MẬT - BỆNH VIỆN BẠCH MAI

Abstract

In recent years, with changes in lifestyle and eating habits, the incidence of AP increases year by year. Determining the cause of pancreatitis is an essential key of the diagnostic evaluation. Different causes can lead to different complications and treatment. Objectives: The etiology of acute pancreatitis, its relationship to some clinical features, severity, and complications of acute pancreatitis. Methods: This retrospective study was carried out at Bach Mai hospital from April 2020 to April 2021, in wich 220 patients with acute pancreatitis were recruited. The etiology of acute pancreatitis was analyzed, its relationship with sex, aging, treatment, severity and clinical outcomes of AP. AP severity was assessed based on adjusted Atlanta scale, CTSI scale and Imrie score at the time of admission. Clinical outcomes included organ failure complication, local complication, ICU admission, median length of stay. Results: The study enrolled 220 patients. causes included gallstones (21, 9.5%), alcohol (108, 49.1%), hypertriglyceridemia (55, 25.0%), and the others (34, 15.45%). Alcoholic AP was the most frequent primary cause. There was higher proportion of alcoholic and hypertriglyceridemic AP in men than in women. Diabetes mellitus were more predominant in hypertriglyceridemic AP (p=0.028). The needs for ICU admission and fluid resuscitation (>3L) were significantly higher in hypertriglyceridemia AP (p=0.000). Severe acute pancreatitis according to Atlanta classification included 18 patients, accounting for 8.2%. There was no significant difference in severity, length of hospital stay, local complications, organ failure between groups of etiologies of acute pancreatitis. Conclusion: Alcoholic AP is the most prevalent etiology of AP. No significantly differences in severity, median length of stay, local complication, organ failure complications were found among groups