STUDY ON EXPERIMENTAL ANTI-INFLAMMATORY EFFECTS OF ANTI ECZEMA CAPSULES

Phạm Thái Hà Văn, Nguyễn Mạnh Tuyển

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Abstract

Objectives: To evaluate the anti-inflammatory effect of anti eczema capsule in rats. Subjects and methods: anti eczema capsule was evaluated the acute anti-inflammatory effect by the method of causing peritoneal effusion by carrageenin and chronic anti-inflammatory effects by the method of causing granulomatous experiments. Results: anti eczema capsule have anti acute inflammatory effect and on the model of peritonitis and anti chronic inflammatory effect on the granulomatous model in rats with the doses of 0.6g/kgBW (equivalent to the clinical dose) and 1,8g/kgBW  (equivalent to three times of the clinical dose) which equivalent to prednisolone dose of 5 mg/kg (p > 0.05). Conclusion: anti eczema capsule show both acute and chronic anti-inflammatory effects in research models in rats.

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References

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