Article Sidebar
Views PDF: 201
STUDY ON EXPERIMENTAL ANTI-INFLAMMATORY EFFECTS OF ANTI ECZEMA CAPSULES
Main Article Content
Abstract
Objectives: To evaluate the anti-inflammatory effect of anti eczema capsule in rats. Subjects and methods: anti eczema capsule was evaluated the acute anti-inflammatory effect by the method of causing peritoneal effusion by carrageenin and chronic anti-inflammatory effects by the method of causing granulomatous experiments. Results: anti eczema capsule have anti acute inflammatory effect and on the model of peritonitis and anti chronic inflammatory effect on the granulomatous model in rats with the doses of 0.6g/kgBW (equivalent to the clinical dose) and 1,8g/kgBW (equivalent to three times of the clinical dose) which equivalent to prednisolone dose of 5 mg/kg (p > 0.05). Conclusion: anti eczema capsule show both acute and chronic anti-inflammatory effects in research models in rats.
Article Details
Keywords
capsule, anti eczema, anti-inflammatory
References
2. Nguyễn Mạnh Tuyển và cs (2015), “Đánh giá tác dụng chống viêm thực nghiệm của cao đặc bào chế từ dịch chiết nước bài thuốc EZ”, Tạp chí dược học, 474, tr. 50-54.
3. Chan BC., Hon KL., Leung PC., Sam SW., Fung KP., Lee MY., Lau HY. (2008), “Traditional Chinese medicine for atopic eczema: PentaHerbs formula suppresses inflammatory mediators release from mast cells”, Ethnopharmacol journal, 120 (1), pp. 85-91.
4. Han T., Li HL., Zhang QY., (2007,), “Bioactivity-guided fractionation for anti-inflammator and analgesic properties and constituents of Xanthium strumarium L.”, Phytomedicine Journal, 14 (12), pp. 825-829.
5. He X., Yajun B., Zefeng Z, (2016), “Local and traditional uses, phytochemistry, and pharmacology of Sophora japonica L.”, Ethnopharmacol Journal, pp. 160-182.
6. Lalrinzuali K., Vabeiryureilai M., Jagetia G.C. (2016), “Investigation of the Anti-Inflammatory and Analgesic Activities of Ethanol Extract of Stem Bark of Sonapatha Oroxylum indicum In Vivo”, International journal of inflammation.
7. Lu H. (2015), “Study on the isolation of active constituents in Lonicera japonica and the mechanism of their anti-upper respiratory tract infection action in children”, African health sciences, 15 (4), pp. 1295-1301.
8. Peng W., Ming Q., Han P., (2014), “Anti- allergic rhinitis effect of caffeoxyl xanthiazonosid isolated from fruits of Xanthiumstrumarium L. in rodent animals”, Phytomedicine journal, 21 (6), pp. 824-829.