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Date Published: 05/07/2023
Abstract Views: 1429
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DOI: https://doi.org/10.51298/vmj.v527i2.5922
Issue
Vol. 527 No. 2 (2023)
Section
Các bài báo
How to Cite
Lê, H. H., Vương, Q. H., Nguyễn, H. V., Nguyễn, V. A., Lê, V. H., Lê, H. D., Vũ, N. M., Nguyễn, T. H. V., Vũ, H. L., & Lê, H. L. H. (2023). PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY OF MYCOPLASMA HOMINIS AND UREAPLASMA SPP. ISOLATED IN NATIONAL HOSPITAL OF DERMATOLOGY AND VENEREOLOGY IN 2021. Vietnam Medical Journal, 527(2). https://doi.org/10.51298/vmj.v527i2.5922

PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY OF MYCOPLASMA HOMINIS AND UREAPLASMA SPP. ISOLATED IN NATIONAL HOSPITAL OF DERMATOLOGY AND VENEREOLOGY IN 2021

Huy Hoàng Lê1, Quang Hà Vương2, Hoàng Việt Nguyễn2, Văn An Nguyễn3, Văn Hưng Lê2,4, Hữu Doanh Lê2,4, Nguyệt Minh Vũ2,4, Thị Hà Vinh Nguyễn2,4, Huy Lượng Vũ2,4, Hạ Long Hải Lê2,4,
1 National Institute of Hygiene and Epidemiology
2 HMU
3 103 Military Hospital
4 National Hospital of Dermatology and Venereology

Main Article Content

Abstract

Mycoplasma hominis and Ureaplasma spp., commonly found in the urogenital tract, have been associated with urogenital infections. Although only a limited number of antibiotics are available to treat these bacteria, antimicrobial resistance has been reported. Methods: This cross-sectional study aimed to investigate the prevalence and antimicrobial resistance of mycoplasmas, including Mycoplasma hominis and Ureaplasma spp., isolated in the National Hospital of Dermatology and Venereology in 2021. Results: Of the 357 genital cultures, 132 (37.0%) were positive for mycoplasmas, with 131 (36.7%) cases of Ureaplasma spp. and 38 (10.6%) cases of M. hominis. Of the 132 positive cases, 71.2% had a single infection of Ureaplasma spp. and 0.8% had a single infection of M. hominis, while 28.0% had a coinfection. The prevalence of mycoplasmas, Ureaplasma spp., and M. hominis was significantly higher in females than in males, and the highest positive rates were observed in patients aged less than 24 years. Ureaplasma spp. had a high susceptibility rate to Pristinamycin, Josamycin, and Doxycycline (98.9%, 96.8%, and 94.7%, respectively), while 78.8% and 52.1% of Ureaplasma spp. isolates were resistant to Ciprofloxacin and Ofloxacin, respectively. Conclusions: This study demonstrates a high prevalence of Ureaplasma spp. compared to M. hominis, with the prevalence of both bacteria being associated with sex and age. Pristinamycin, Josamycin, and Doxycycline show promise as effective antibiotics for the urogenital treatment of Ureaplasma spp. and M. hominis.

Article Details

Keywords

Mycoplasma hominis, Ureaplasma, resistance, prevalence.

References

1. Bartolini, A., et al. (2017), Prevalence and antimicrobial susceptibility of genital Mycoplasmas detected by Mycoplasma IST 2 from urogenital samples in Padua, Italy, between January 2014 and December 2015. Microbiologia Medica. 32(1).
2. Beeton, M.L., et al. (2016), Antibiotic Resistance among Clinical Ureaplasma Isolates Recovered from Neonates in England and Wales between 2007 and 2013. Antimicrob Agents Chemother. 60(1): p. 52-6.
3. Foschi, C., et al. (2018), Prevalence and antimicrobial resistance of genital Mollicutes in Italy over a two-year period. New Microbiol. 41(2): p. 153-158.
4. Jang, Y.S., J.W. Min, and Y.S. Kim (2019), Positive culture rate and antimicrobial susceptibilities of Mycoplasma hominis and Ureaplasma urealyticum. Obstet Gynecol Sci. 62(2): p. 127-133.
5. Kasprzykowska, U., et al. (2018), A twelve-year retrospective analysis of prevalence and antimicrobial susceptibility patterns of Ureaplasma spp. and Mycoplasma hominis in the province of Lower Silesia in Poland. Eur J Obstet Gynecol Reprod Biol. 220: p. 44-49.
6. Lee, J.Y. and J.S. Yang (2020), Prevalence and Antimicrobial Susceptibility of Mycoplasma hominis and Ureaplasma Species in Nonpregnant Female Patients in South Korea Indicate an Increasing Trend of Pristinamycin-Resistant Isolates. Antimicrob Agents Chemother. 64(10).
7. Schneider, S.C., et al. (2015), Antibiotic Susceptibility and Sequence Type Distribution of Ureaplasma Species Isolated from Genital Samples in Switzerland. Antimicrob Agents Chemother. 59(10): p. 6026-31.
8. Song, J., et al. (2022), Prevalence and antibiotics resistance of Ureaplasma species and Mycoplasma hominis in Hangzhou, China, from 2013 to 2019. Front Microbiol. 13: p. 982429.