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ASSESSMENT OF THE BREAST PAPILLARY LESSIONS AND SOME CLINICOPATHOLOGICAL FEATURES
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Abstract
Papillary lesions only account for 2% of the mammary lesions, but this lesion ownes many features that can confuse between benign, atypical and malignant characteristic in the diagnosis, classification and treatment. Purpose: Comment on some clinical features, histopathology and immunohistochemistry of papillary lesions in breast. Methods: 79 patients with papillary lesion were classified in histopathological subgroups by WHO classification, reviewing some clinicopathological characteristics, IHC stain of Ki67 marker. Results: 100% intraductal papilloma has a low Ki67. Atypical papillary lesion group was seen in 1 case with a high Ki67 score (p <0.05). In the group of malignant papillary lesions, there were 5 cases with high Ki67, mainly seen in type of encapsulated papillary carcinoma (p <0,05). Conclusion: ADH and DCIS were more common in the group of papillary carcinoma than intraductal papilloma, and the likelihood of developing papillary carcinoma of the ADH group was 6.5 times higher than in the lession without ADH.
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Keywords
Breast Papillary lesion, Clinicopathological feature, Immunohistochemistry
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