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Date Published: 18/07/2023
Abstract Views: 517
Views PDF: 280
DOI: https://doi.org/10.51298/vmj.v528i1.6025
Issue
Vol. 528 No. 1 (2023)
Section
Các bài báo
How to Cite
Thân, M. H., Vũ, Đình P., & Lê, V. N. (2023). THE ANTIBIOTIC RESISTANCE AND RESISTANCE GENES OF STREPTOCCOCUS SUIS IN HUMAN. Vietnam Medical Journal, 528(1). https://doi.org/10.51298/vmj.v528i1.6025

THE ANTIBIOTIC RESISTANCE AND RESISTANCE GENES OF STREPTOCCOCUS SUIS IN HUMAN

Mạnh Hùng Thân1,2,, Đình Phú Vũ1,2, Văn Nam Lê3
1 National Hospital of Tropical Diseases
2 University of Medicine and Pharmacy - Hanoi National University
3 103 Military Hospital

Main Article Content

Abstract

Background: Streptococcus suis (S. suis) is a human pathogen that causes a number of diseases and has the ability to spread epidemics with significant fatality rates, particularly in septic shock patients. Objectives: To analyze antibiotic resistance and the expression of drug resistance genes of S. suis in human. Methods: A prospective, observational study to analysis of the antibiotic resistance of S. suis by E-test technique and resistance genes of S. suis. Results: 90% of patients were male. S. suis strains were completely susceptible to penicillins, ampicillin, ceftriaxone, linezolid, and vancomycin. Antibiotics with a high rate of resistance were erythromycin (76.3%), clindamycin (73.5%), and tetracycline (97.6%). Antibiotic resistance genes included: ant(6),  tet(B),  tet(O), and erm(B) with prevalence of 78.75%, 75%, 28.75%, and 60%, respectively. Conclusion: S. suis has remained resistant to commonly used antibiotics such as penicillin, ampicillin, and ceftriaxone. There was an association of the frequency of resistance genes and antibiotic resistance on the antibiogram.

Article Details

Keywords

Streptococcus suis, S. suis resistance gene

References

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