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Date Published: 07/08/2023
Abstract Views: 153
Views PDF: 107
DOI: https://doi.org/10.51298/vmj.v528i2.6101
Issue
Vol. 528 No. 2 (2023)
Section
Các bài báo
How to Cite
Đàm, T. T. H., Nguyễn, H. D., Nguyễn, Q. H., Nguyễn, T. L. H., Đỗ, G. T., Đặng, T. V. H., Đỗ, T. M., & Trịnh, T. L. (2023). EVALUATE THE ASSOCIATION BETWEEN MEDICATION ADHERENCE AND TACROLIMUS INTRA-PATIENT VARIABILITY (IPV) IN PATIENTS AFTER KIDNEY TRANSPLANTATION AT BACH MAI HOSPITAL. Vietnam Medical Journal, 528(2). https://doi.org/10.51298/vmj.v528i2.6101

EVALUATE THE ASSOCIATION BETWEEN MEDICATION ADHERENCE AND TACROLIMUS INTRA-PATIENT VARIABILITY (IPV) IN PATIENTS AFTER KIDNEY TRANSPLANTATION AT BACH MAI HOSPITAL

Thị Thu Hằng Đàm1, Hữu Duy Nguyễn2, Quỳnh Hoa Nguyễn1, Thị Liên Hương Nguyễn2,, Gia Tuyển Đỗ1, Thị Việt Hà Đặng1, Trường Minh Đỗ1, Tố Linh Trịnh1
1 Bach Mai Hospital
2 Hanoi University of Pharmacy

Main Article Content

Abstract

Objectives: This study aims to evaluate immunosuppressive medication adherence and the association between medication adherence and tacrolimus intra-patient variability (IPV) in patients after kidney transplantation at Bach Mai hospital. Subjects and methods: Cross-sectional study, interview patients using immunosuppressive therapy after kidney transplantation. Information on medical history, drug history, treatment regimens, adverse events, and tacrolimus trough concentrations were collected from outpatient medical records. The BAASIS questionnaire was used to assess medication adherence. Results: The percentage of patients who missed at least 1 dose and took the wrong time administration during 4 weeks was 51.8% and 47.8%, respectively. The percentage of medication adherence in the study was 23.2%. tacrolimus IPV in the adherence patients (33.6 ± 7.9) was lower than that of non-adherent patients (39.5 ± 10.2) (p < 0.001). Conclusion: The majority of patients in the study were non-adherent. Immunosuppressive medication adherence was associated with lower tacrolimus IPV.

Article Details

Keywords

Medication adherence, immunosuppressive medication, kidney transplatation

References

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