CLINICAL AND ECHOCARDIOGRAPHY CHARACTERISTICS IN PATIENTS WITH EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Lân Hiếu Nguyễn1,2, Duy Thắng Nguyễn1,2,, Thu Phương Phan1
1 HMU
2 Hanoi Medical University Hospital

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Abstract

Chronic Obstructive Pulmonary Disease (COPD) is a common disease, that involves hospitalized exacerbations. Patients may have comorbidities and be led to pulmonary hypertension, right and even left ventricular heart failure. This study was conducted on 103 patients with exacerbation of COPD (91.26% men; mean age 73.11 ± 9.51) to evaluate their clinical and echocardiography characteristics. Most common reasons of hospitalization were dyspnea (95.09%). Most patients had infection (95.15%). Cardiovascular diseases were the most popular comorbidities (66.02%). 70.84% of patients has one or more other comorbidities. Mean Pulmonary artery systolic pressure (PAPS)  was 40.21 ± 12.35 mmHg. 75.73% of patients had pulmonary hypertension, among proportion of mild, medium and severe PH were 57.28%, 16.50 and 1.94%, respectively. 9.71% of cases had Right ventricular systolic dysfunction with FAC < 35 and/or TAPSE<16mm. 5.83% of patients had left ventricular systolic dysfunction with LVEF<50%. There was a linear negative correlation between PAPS and TAPSE, p=0.005

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References

1. Groff P, Petrelli G, Giorgini P, Pilotti R, Parato VM, Fabbri A. Clinical heterogeneity of a population of patients admitted to the Emergency Department with a diagnosis of COPD-exacerbation: Relevance of cardiovascular comorbidities. Emerg Care J. 2021;17(1). doi:10.4081/ecj.2021.9502
2. Agusti A, Calverley PM, Celli B, et al. Characterisation of COPD heterogeneity in the ECLIPSE cohort. Respir Res. 2010;11(1):122. doi:10.1186/1465-9921-11-122
3. Alvar Agusti, Richard Beasley, Bartolome R. Celli, et al,. Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease 2020 REPORT. Published 2020. Accessed October 8, 2020. https://goldcopd.org/wp-content/uploads/ 2019/11/GOLD-Pocket-Guide-2020-final-wms.pdf
4. Ngô Quý Châu. Bệnh phổi tắc nghẽn mãn tính. In: Bệnh Học Nội Khoa. Vol Tập 1. ; 2020:trang 20-49.
5. Gupta NK, Agrawal RK, Srivastav AB, Ved ML. Echocardiographic evaluation of heart in chronic obstructive pulmonary disease patient and its co-relation with the severity of disease. Lung India Off Organ Indian Chest Soc. 2011; 28(2):105-109. doi:10.4103/0970-2113.80321
6. Gut-Gobert C, Cavaillès A, Dixmier A, et al. Women and COPD: do we need more evidence? Eur Respir Rev. 2019;28(151). doi:10.1183/ 16000617.0055-2018
7. Landis SH, Muellerova H, Mannino DM, et al. Continuing to Confront COPD International Patient Survey: methods, COPD prevalence, and disease burden in 2012-2013. Int J Chron Obstruct Pulmon Dis. 2014;9:597-611. doi:10.2147/ COPD.S61854
8. Van Minh H, Giang KB, Ngoc NB, et al. Prevalence of tobacco smoking in Vietnam: findings from the Global Adult Tobacco Survey 2015. Int J Public Health. 2017;62(Suppl 1):121-129. doi:10.1007/s00038-017-0955-8
9. Vanfleteren LEGW, Spruit MA, Groenen M, et al. Clusters of comorbidities based on validated objective measurements and systemic inflammation in patients with chronic obstructive pulmonary disease. Am J Respir Crit Care Med. 2013;187(7):728-735. doi:10.1164/rccm.201209-1665OC
10. Ongel EA, Karakurt Z, Salturk C, et al. How do COPD comorbidities affect ICU outcomes? Int J Chron Obstruct Pulmon Dis. 2014;9:1187-1196. doi:10.2147/COPD.S70257