ĐÁNH GIÁ THAY ĐỔI MỘT SỐ YẾU TỐ ĐÔNG MÁU Ở BỆNH NHÂN SỐC NHIỄM KHUẨN

Abstract

Objectives: To survey the change of some coagulation parameter septic shock patients. Materials and method: Prospective Descriptive Study on 30 septic shock patients treated in the Centre of Emergency, Intensive Care Medicine and Clinical Toxicology – 103 Military Hospital – Vietnam Military Medical University. Result: The male/female ratio was 1.5, average age of 61,4 ± 17,3 Where as 46,7% had co - disease. Death rate is 46,7% (14). The lowest platelet count at the 3^rd day (121 ± 85,8) and at the 5^th, 7^th day of the dead group was lower than the survivor group statistical significance (p<0,05). The PT% of the dead group was 70% lower than at the time of diagnosis sepsis shock, then gradually decrease on the next day and reached the lowest on the 7^th day (48 ± 29,8%) clearly low when compared to the survivor group at the 5^th, 7^th day (p>0,05). Similar to APTTs extended more than 42s straight at the time of dianogsis, continued increase in the following day and reached the highest at the 7^th day (60,15 ± 43,2s) and to compared to the survivor group, it’s significance different (p>0,05) at the 7^th day. DIC score > 5 and gradually increased in the whole 5 times of study, reached the highest at the 7^th day (5,9 ± 1,3) of the dead group and higher than the survivor group statistical significance at the 5^th, 7^th day. Conclusions: The sepsis shock patients of the dead group have the platelet count and PT% index tended to decrease gradually, APTTs time was prolonged over the study period and there is statistically significance difference compare to the survivor group at the 5^th and 7^th day. To go abreast with that is the DIC score > 5 at all over the time of study and clearly different when compare to the survivor group at the 7^th day