ĐẶC ĐIỂM LÂM SÀNG THEO TỔN THƯƠNG MÔ BỆNH HỌC CỦA VIÊM DẠ DÀY MẠN TÍNH CÓ NHIỄM HELICOBACTER PYLORY Ở TRẺ EM TẠI BỆNH VIỆN SẢN NHI NGHỆ AN

Abstract

Chronic gastritis caused by H. pylori is a public health problem. Histopathological test of gastric mucosa biopsies plays an important role in the diagnosis of chronic gastritis and H. pylori infection. Aim: Describe the clinical characteristics according to histopathological lesions of chronic gastritis with H. pylori infection in children at Nghe An Obstetric & Pediatric Hospital. Materials and methods: A cross-sectional description study conducted in patients diagnosed with positive H. pylori chronic gastritis at Nghe An Obstetric & Pediatric Hospital from 01/07/2022 to 31/03/2023. Results: Female/male ratio was 1.12/1, mean age was 9.3 ± 2.7 years (3 - 15 years). Endoscopic findings showed prevalence of erythematous, nodularity and hyperplastic was 96.5%; 60.0% and 2.4%, respectively. Rate of H. pylori infection in histology examination was 42.4% for mild infection. Prevalence of moderate and severe infection was 24.7% and 58.9%, respectively. Rate of severe, moderate and mild activity level was 18.8%, 32,9% and 45.9%, respectively. There was an association between belching - heartburn and gastrointestinal bleeding with severe H. pylori infection (OR: 8.77 and 8.77, respectively), severe inflammation (OR: 8.17 and 6.00, respectively), and severe activity level (OR: 3.46 and 3.60, respectively). Conclusions: Most of patients have mild H. pylori infection, moderate chronic gastritis, mild activity. There was an association between belching - heartburn, and gastrointestinal bleeding with severe H. pylori infection, inflammation and activity level